Results 261 to 270 of about 1,019,622 (327)

Advanced Cancer Immunotherapy via SMARCAL1 Blockade Using a Glucose‐Responsive CRISPR Nanovaccine

Advanced Science, EarlyView.
A glucose‐catalyzed chemodynamic strategy is proposed to activate therapeutic genome editing of SMARCAL1to improve cancer immunotherapy. This innovative design featuring Fenton reaction activity and glucose consumption ability, not only effectively synergizes to activate the cGAS‐STING pathway but also inhibits the opposing functions of interferon by ...
Yuwei Li, Yuanyi Zhang, Chenchen Li, Guoping Chen, Pir Muhammad, Yonghong Yao, Lifang Gao, Zhigang Liu, Yanli Wang   +8 more
wiley   +1 more source

Contrast-enhanced harmonic EUS with time-intensity curve analysis useful for diagnosis of pancreatic metastasis from renal cell carcinoma (with videos). [PDF]

Endosc Ultrasound
Saima A, Kazumori H, Tsunoda H, Onishi K, Kawashima K.   +4 more
europepmc   +1 more source

The relationship of serum CEA and CA 19-9 levels to liver metastasis and pancreatic invasion in esophageal cancer

, 2009
Atila Türkyılmaz, Atilla Eroğlu, Yener Aydın, Nurettin Karaoğlanoğlu   +3 more
openalex   +2 more sources

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

A rare case of MET exon 14 skipping mutation-positive pulmonary sarcomatoid carcinoma with pancreatic metastasis. [PDF]

Respir Med Case Rep
Hayashi T, Otani S, Kitazawa R, Ueki T, Ishimura T, Sugihara T, Ogura F, Kiriyama Y, Mori Y, Sakao N, Sano Y, Izutani H.   +11 more
europepmc   +1 more source

Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer

, 2009
Jennifer M. Bailey, Alicia M. Mohr, Michael A. Hollingsworth   +2 more
openalex   +1 more source

LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5

Advanced Science, EarlyView.
Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li, Zhuo‐Ran Liang, Zhi‐Chao Liu, Xue‐Ping Luo, Jun‐Yi Li, Xiao‐Mei Yu, Xuan‐Zhang Huang, Yan He, Tao‐Yang Xu, Jiao‐Jiao Xu, Shao‐Cong Peng, Yu‐Xiang Song, Yan He, Xiao‐Wan Zhuang, Can‐Can Zheng, Fan Zhang, Alfred King‐Yin Lam, Wei Dai, Ming‐Liang He, Bo Liu, Qi Zhao, Guo‐Liang Lu, Jin‐Bao Liu, Zhen‐Ning Wang, Zhi‐Gang Li, Ze‐Xian Liu, Wen‐Wen Xu, Bin Li   +27 more
wiley   +1 more source

A Case of Nonfunctional Pancreatic Endocrine Tumor with Splenic Metastasis

, 2009
Keiko Hamasaki, Takayuki NAKAZAKI, Kaori Shimizu, Hisakazu Shindo, Isao Sano, Hideki Taniguchi, Osamu Takahara   +6 more
openalex   +2 more sources

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Pancreatic metastasis from renal cell carcinoma

, 2009
Bálint Botz, Natalie Yang
openalex   +1 more source