Results 21 to 30 of about 265,491 (183)
Invasion and metastasis in pancreatic cancer
Annals of Oncology, 1999 Understanding the molecular mechanisms of invasion and metastasis is crucial for the development of novel therapeutic strategies to treat metastases. Considerable studies revealed that the establishment of metastasis is the final outcome of a series of processes such as tumor growth, angiogenesis, tumor cell detachment and invasion of extracellular ...
V, Ellenrieder, G, Adler, T M, Gress
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High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models. [PDF]
, 2016 Liver metastasis is the main cause of colon cancer-related death and is a recalcitrant disease. We report here the efficacy and safety of intra-portal-vein (iPV) targeting of Salmonella typhimurium A1-R on colon cancer liver metastasis in a nude-mouse ...
Bouvet, Michael +11 more
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Pancreatic Metastasis from Prostate Cancer [PDF]
Case Reports in Medicine, 2010 The pancreas is an unusual location for metastases from other primary cancers. Rarely, pancreatic metastases from kidney or colorectal cancers have been reported. However, a variety of other cancers may also spread to the pancreas. We report an exceptional case of pancreatic metastasis from prostate cancer. Differences in management between primary and
Julian Jacob +7 more
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Treatment options for PNET liver metastases. a systematic review [PDF]
, 2018 Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo +8 more
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Thymoma metastatic to liver and pancreas: case report and review of the literature [PDF]
, 2017 A 71-year-old man presented with a thymic mass involving the superior vena cava. A mediastinoscopical biopsy initially suggested a diagnosis of type A thymoma.
Blandamura, Stella +4 more
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Role of Fibroblast Growth Factor Receptor 2 in Pancreatic Cancer: Potential Target for New Therapeutic Approach? [PDF]
, 2015 Fibroblast growth factors and their receptors play a key role in cell proliferation, migration and differentiation. Fibroblast growth factor receptor 2 (FGFR2) is involved in carcinogenesis and its altered expression has been shown in several tumors ...
Angeloni, Antonio +2 more
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Epigenetic control of pancreatic cancer metastasis
Cancer and Metastasis Reviews, 2023 AbstractSurgical resection, when combined with chemotherapy, has been shown to significantly improve the survival rate of patients with pancreatic ductal adenocarcinoma (PDAC). However, this treatment option is only feasible for a fraction of patients, as more than 50% of cases are diagnosed with metastasis.
Krauß, Lukas +4 more
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Hyperglycemia as a mechanism of pancreatic cancer metastasis
Frontiers in Bioscience, 2012 As a vital step in the progression of cancer, metastasis poses the largest problem in cancer treatment and is the main cause of death of cancer patients. In pancreatic cancer, almost 80% of patients have locally deteriorated or metastatic disease and thus are not appropriate for resection at the time of diagnosis.
Wei, Li +8 more
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, 2001 Matrix metalloproteinases (MMPs) is a family of collagenolytic enzymesand are associated with many pathological conditions. Especially, MMPs have a strong relation with tumor progression and invasion. In this review, we focused on association of MMPs and
Ichimura, Mitsuko +6 more
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Stress Proteins and Pancreatic Cancer Metastasis [PDF]
The Scientific World JOURNAL, 2010 Tumor metastasis is challenged by its resistance to microenvironmental stress infringed during escape from the primary tumor and the colonization of a foreign secondary tissue. Because of its great metastatic potential and its strong resistance to anticancer drugs, pancreatic cancer is regarded as a paradigm of the adaptation of cancer cells to ...
Carla E. Cano, Juan L. Iovanna
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