Results 41 to 50 of about 247,170 (323)
Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer [PDF]
, 2019 York University ...
Bhattacharya, Debasmita, Scimè, Anthony
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Invasion and metastasis in pancreatic cancer
Annals of Oncology, 1999 Understanding the molecular mechanisms of invasion and metastasis is crucial for the development of novel therapeutic strategies to treat metastases. Considerable studies revealed that the establishment of metastasis is the final outcome of a series of processes such as tumor growth, angiogenesis, tumor cell detachment and invasion of extracellular ...
Thomas M. Gress +2 more
openaire +3 more sources
LncRNAs as epigenetic regulators of epithelial to mesenchymal transition in pancreatic cancer
Discover Oncology, 2022 Pancreatic cancer is the leading cause of cancer-related mortality because of tumor metastasis. Activation of the epithelial-to-mesenchymal transition (EMT) pathway has been confirmed to be an important driver of pancreatic cancer progression from ...
Yan Ma +9 more
doaj +1 more source
Treatment options for PNET liver metastases. a systematic review [PDF]
, 2018 Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo +8 more
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Annals of Gastroenterological Surgery, 2022 Aim The appropriate extent of lymphadenectomy for pancreatic cancer of the body/tail has not been standardized worldwide. The present study evaluated the optimal extent of harvesting lymph nodes.
Takuya Minagawa +8 more
doaj +1 more source
Case Reports in Medicine, 2014 We present a case report of a 75-years-old woman affected by renal clear cell carcinoma with a synchronous pancreatic metastasis and a metachronous lung metastasis. This case has two peculiarities.
Salvatore Lauro +5 more
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Cell Death and Disease, 2023 Pancreatic cancer is a leading cause of cancer death due to its early metastasis and limited response to the current therapies. Metastasis is a complicated multistep process, which is determined by complex genetic alterations.
Fang Cao +11 more
doaj +1 more source
Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis [PDF]
The American Journal of Pathology, 2010 Pancreatic stellate cells (PSCs) produce the stromal reaction in pancreatic cancer (PC), and their interaction with cancer cells facilitates cancer progression. This study investigated the role of human PSCs (hPSCs) in the metastatic process and tumor angiogenesis using both in vivo (orthotopic model) and in vitro (cultured PSC and PC cells) approaches.
Jeremy S. Wilson +10 more
openaire +3 more sources
High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models. [PDF]
, 2016 Liver metastasis is the main cause of colon cancer-related death and is a recalcitrant disease. We report here the efficacy and safety of intra-portal-vein (iPV) targeting of Salmonella typhimurium A1-R on colon cancer liver metastasis in a nude-mouse ...
Bouvet, Michael +11 more
core +3 more sources
Metastasis to the pancreas and the spleen: an increasing diagnostic and therapeutic challenge
Clinics and Practice, 2011 We have reviewed the electronic biopsies database files of the Department of Surgical Pathology, Fundación Jiménez Díaz in Madrid (Spain). In this time period (1998-2010) we have found 3 pancreatic metastasis and 5 splenic metastasis.
Peter Wolfgang Vorwald +3 more
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