Results 41 to 50 of about 152,984 (289)

Liver metastasis composed of pure squamous cell carcinoma component from pancreatic pure ductal adenocarcinoma: a case report

Surgical Case Reports, 2023
Background Liver metastasis of pure squamous cell carcinoma (SCC) from pancreatic ductal adenocarcinoma has not been previously reported. Case presentation A 66-year-old man underwent a computed tomography scan 3 years after surgery for pancreatic head ...
Yohei Mano, Keishi Sugimachi, Tomonari Shimagaki, Takahiro Tomino, Emi Onishi, Lingaku Lee, Terumasa Hisano, Yutaka Koga, Kenichi Taguchi, Masaru Morita, Yasushi Toh   +10 more
doaj   +1 more source

Prediction scores of postoperative liver metastasis and long‐term survival of pancreatic head cancer based on the distance between the mesenteric vessels and tumor, preoperative serum carbohydrate antigen 19‐9 level, and lymph node metastasis rate

Cancer Medicine, 2023
Background The shortest distance between the superior mesenteric artery (SMA) or superior mesenteric vein (SMV) and the tumor margin was combined with preoperative serum carbohydrate antigen (CA) 19‐9 and lymph node ratio (LNR) to evaluate joint effects ...
Dan Jiang, Xiaona Fan, Pengfei Li, Yang Zhou, Kaige Chen, Hengzhen Li, Jinshuang Liu, Wenjing Zhang, Yisheng Dai, Ning Sun, Zhiwei Li   +10 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Targeted intervention of eIF4A1 inhibits EMT and metastasis of pancreatic cancer cells via c-MYC/miR-9 signaling

Cancer Cell International, 2021
Background Owing to the lack of effective treatment options, early metastasis remains the major cause of pancreatic ductal adenocarcinoma (PDAC) recurrence and mortality. However, the molecular mechanism of early metastasis is largely unknown.
Yuchong Zhao, Yun Wang, Wei Chen, Shuya Bai, Wang Peng, Mengli Zheng, Yilei Yang, Bin Cheng, Zhou Luan   +8 more
doaj   +1 more source

Pancreatic neuroendocrine carcinoma metastasis to the skin

Endokrynologia Polska, 2021
Not required for Clinical Vignette.
Joanna Pilch-Kowalczyk, Bartosz Molasy, Anna Zemczak, Katarzyna Kuśnierz, Weronika Szczęsny-Karczewska   +4 more
openaire   +4 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Targeting cancer-related inflammation: Chinese herbal medicine inhibits epithelial-to-mesenchymal transition in pancreatic cancer. [PDF]

PLoS ONE, 2013
Pancreatic cancer is an almost universally fatal disease resulting from early invasion of adjacent structures and metastasis and the lack of an effective treatment modality.
Juan Zhang, Peng Wang, Huaqiang Ouyang, Jianhua Yin, Aihua Liu, Chunzheng Ma, Luming Liu   +6 more
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Pancreatic Metastasis of Breast Cancer: A Rare Cause of Obstructive Jaundice

Journal of the Dow University of Health Sciences, 2015
The pancreas is a rare site of metastasis from malignant tumours. Pancreatic metastasis accounts for less than 5% of all pancreatic malignancies. The most common malignancies metastasizing to pancreas are the renal cell carcinoma, non-small cell lung ...
Mutahir A. Tunio, Hanadi Fatani, Khalid Riaz, Mushabbab AlAsiri   +3 more
doaj   +4 more sources