Results 51 to 60 of about 273,218 (326)

Tumor microenvironment participates in metastasis of pancreatic cancer

Molecular Cancer, 2018
Pancreatic cancer is a deadly disease with high mortality due to difficulties in its early diagnosis and metastasis. The tumor microenvironment induced by interactions between pancreatic epithelial/cancer cells and stromal cells is critical for ...
Bo Ren, Ming Cui, Gang Yang, Huanyu Wang, Mengyu Feng, Lei You, Yupei Zhao   +6 more
doaj   +1 more source

Solitary pancreatic renal cell carcinoma metastasis [PDF]

Autopsy and Case Reports, 2018
Pancreatic metastases are rare; they account for only 2% of all pancreatic malignancies and usually occur when associated with a disseminated metastatic disease. Solitary pancreatic metastases are even less frequent, and there are few reports regarding surgical resection.
Miguel Nogueira, Sílvia Costa Dias, Ana Catarina Silva, João Pinto, Jorge Machado   +4 more
openaire   +3 more sources

Targeted intervention of eIF4A1 inhibits EMT and metastasis of pancreatic cancer cells via c-MYC/miR-9 signaling

Cancer Cell International, 2021
Background Owing to the lack of effective treatment options, early metastasis remains the major cause of pancreatic ductal adenocarcinoma (PDAC) recurrence and mortality. However, the molecular mechanism of early metastasis is largely unknown.
Yuchong Zhao, Yun Wang, Wei Chen, Shuya Bai, Wang Peng, Mengli Zheng, Yilei Yang, Bin Cheng, Zhou Luan   +8 more
doaj   +1 more source

Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis [PDF]

, 2018
Pancreatic cancer, mostly pancreatic ductal adenocarcinoma (PDAC), is one of the most lethal cancer types, with an estimated 44,330 death in 2018 in the US alone.
Chen, Shaoxiong, Fan, Qipeng, Gu, Dongsheng, Lin, Hai, Liu, Yunlong, Shahda, Safi, Sun, Jie, Xie, Jingwu, Zhang, Xiaoli   +8 more
core   +1 more source

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source

Thymoma metastatic to liver and pancreas: case report and review of the literature [PDF]

, 2017
A 71-year-old man presented with a thymic mass involving the superior vena cava. A mediastinoscopical biopsy initially suggested a diagnosis of type A thymoma.
Blandamura, Stella, Passuello, Nicola, Pozza, Gioia, Sperti, Cosimo, Valmasoni, Michele   +4 more
core   +1 more source

Pancreatic Metastasis of Breast Cancer: A Rare Cause of Obstructive Jaundice

Journal of the Dow University of Health Sciences, 2015
The pancreas is a rare site of metastasis from malignant tumours. Pancreatic metastasis accounts for less than 5% of all pancreatic malignancies. The most common malignancies metastasizing to pancreas are the renal cell carcinoma, non-small cell lung ...
Mutahir A. Tunio, Hanadi Fatani, Khalid Riaz, Mushabbab AlAsiri   +3 more
doaj   +4 more sources

DCM-Net: dual-encoder CNN-Mamba network with cross-branch fusion for robust medical image segmentation

BMC Medical Imaging
Background Medical image segmentation is a critical task for the early detection and diagnosis of various conditions, such as skin cancer, polyps, thyroid nodules, and pancreatic tumors.
Chukwuemeka Clinton Atabansi, Sheng Wang, Hui Li, Jing Nie, Lei Xiang, Cheng Zhang, Haijun Liu, Xichuan Zhou, Dewei Li   +8 more
doaj   +1 more source

Updated management of malignant biliary tract tumors: an illustrative review [PDF]

, 2016
The management of malignant biliary tumors (MBTs) is complex and requires a multidisciplinary approach. Guidelines and methods of staging for biliary tumors have recently been released by main international societies, altering the clinical and radiologic
Cannavale, Alessandro, Catalano, Carlo, Fanelli, Fabrizio, Fiocca, Fausto, Gazzetti, Marianna, Maher, Ben, Santoni, Mariangela   +6 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source