Results 91 to 100 of about 114,713 (318)

Randomized preclinical study of machine perfusion in vascularized composite allografts

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin   +7 more
wiley   +1 more source

Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
CD161 is identified as a novel inhibitory receptor on bone marrow (BM)‐resident CD8⁺ T cells in multiple myeloma (MM). Through interaction with its ligand CLEC2D, CD161 impairs T‐cell function and promotes immune suppression. Blockade of CD161 restores tissue residency and cytotoxicity of CD8⁺ T cells and enhances chimeric antigen receptor T‐cell (CAR ...
Liwen Wang   +16 more
wiley   +1 more source

Treatment of acute complicated pancreatic pseudocysts

open access: yesJournal of Education, Health and Sport, 2017
The results of surgery in 70 patients with acute complicated pancreatic pseudocysts in age from 21 to 79 years were analyzed. For patients using an individualized medical – diagnostic campaign, which primarily was aimed at the elimination of ...
I. A. Kryvoruchko   +2 more
doaj  

Features of Ultrasonographic Anatomy and Manifestations of Local Complications in Acute Necrotizing Pancreatitis

open access: yesИнновационная медицина Кубани
Relevance: Diagnosing pancreatic necrosis and its complications is challenging despite the widespread use of state-of-the-art highprecision imaging methods in routine practice.Objective: To determine topographic features of local complications of ...
Olga A. Tseneva   +6 more
doaj   +1 more source

Trans fatty acids increase nitric oxide levels and pancreatic beta-cell necrosis in rats [PDF]

open access: yesUniversa Medicina, 2013
Background The prevalence of diabetes in Indonesia is increasing due to various factors, including life style changes such as trans fatty acid (TFA) intake.
Kusmiyati Tjahjono DK   +2 more
doaj  

Synergistic Anti‐Cancer Therapy Through Ultrasound‐Induced Piezocatalytic Therapy and Tumor Treatment Fields

open access: yesAdvanced Science, EarlyView.
A novel, wearable anti‐cancer platform synergistically combines tumor treating fields (TTFs) and piezocatalytic therapy (PCT) via ultrasound‐activated, lead‐free piezocomposites. This strategy efficiently suppresses tumor growth, modulates the immune microenvironment, and demonstrates strong therapeutic synergy in both mouse model of subcutaneous tumor
Jing Jin   +9 more
wiley   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

open access: yesAdvanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong   +5 more
wiley   +1 more source

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