Pancreatic cancer cachexia: a review of mechanisms and therapeutics. [PDF]
, 2014 Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge.
Andrew Eugene Hendifar +8 more
core +2 more sources
Interactions of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) with the Immune System: Implications for Inflammation and Cancer [PDF]
, 2019 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL has historically been distinct from the Fas ligand and TNFα in terms of selective apoptosis induction in tumor cells and has a nearly non ...
Baukloh, Ann-Kathrin +5 more
core +1 more source
Clinical and Translational Gastroenterology, 2018 Background: Organ failure determines outcome in acute pancreatitis (AP). It is controversial if infected pancreatic necrosis (IPN) is also an independent determinant of mortality.
DM Saransh Jain MD +4 more
semanticscholar +1 more source
Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model. [PDF]
, 2016 A patient with high grade undifferentiated pleomorphic soft-tissue sarcoma from a striated muscle was grown orthotopically in the right biceps femoris muscle of mice to establish a patient-derived orthotopic xenograft (PDOX) model.
Bouvet, Michael +18 more
core +3 more sources
Cancer Medicine, 2023 Background It has been proven that tumor necrosis is associated with poor prognoses in various solid malignant tumors. However, the prognostic effect of tumor necrosis in hepato‐biliary‐pancreatic cancers is still unclear.
Siqi Yang +6 more
doaj +1 more source
Systematic Review with Trial Sequential Analysis of Prophylactic Antibiotics for Acute Pancreatitis
Antibiotics, 2022 Background/Objectives: Prophylactic antibiotics (PAB) are being still widely used for treatment of acute pancreatitis (AP) despite trials showing no firm evidence of efficacy. We aimed to evaluate effects of PAB for AP in a meta-analysis and the need for
Goran Poropat +5 more
doaj +1 more source
Early prediction of infected pancreatic necrosis secondary to necrotizing pancreatitis
Medicine, 2017 To assess the association between the clinical parameters within 48 hours of admission and the occurrence of infected pancreatic necrosis (IPN) during the late phase of necrotizing pancreatitis (NP).
Hongze Chen +6 more
semanticscholar +1 more source
Неотложная медицинская помощь, 2022 Percutaneous interventions for the purpose of sanation of cavities of pancreatogenic destruction can be one of the ways to treat pancreatic necrosis. This leads to a rapid cleansing of the cavities and is an objective method of monitoring the stages of ...
M. L. Rogal +7 more
doaj +1 more source
Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model. [PDF]
, 2017 An excessive requirement for methionine termed methionine dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by methionine deprivation such as with recombinant ...
Chmielowski, Bartosz +15 more
core +2 more sources
The EndoRotor, a novel tool for the endoscopic management of pancreatic necrosis
Endoscopy, 2018 Acute pancreatitis may run a severe course when pancreatic necrosis becomes infected, with mortality rates of up to 30% [1–3]. Endoscopic drainage and ensuing necrosectomy have been shown to be effective in the management of pancreatic necrosis [4, 5 ...
S. E. van der Wiel +4 more
semanticscholar +1 more source