Results 31 to 40 of about 114,713 (318)

Acute Pancreatitis (A Clinical Case)

Креативная хирургия и онкология
ntroduction. The diagnosis of acute pancreatitis poses no significant difficulties. Nonetheless, accurately predicting the potential severity of the disease during its early stages remains a challenge with existing diagnostic methods.
A. I. Khripun, A. N. Alimov, S. Yu. Orlov, T. P. Chelyapina   +3 more
doaj   +1 more source

Open necrosectomy in acute pancreatitis–obsolete or still useful?

World Journal of Emergency Surgery, 2020
Background Multiple organ failure and early surgery are associated with high morbimortality after open necrosectomy. Data are mostly derived from historical cohorts with early necrosectomy bereft of step-up treatment algorithm implementation.
Henrik Leonard Husu, Jouni Antero Kuronen, Ari Kalevi Leppäniemi, Panu Juhani Mentula   +3 more
doaj   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Necrotizing Pancreatitis: Current Management and Therapies [PDF]

Clinical Endoscopy, 2017
Acute necrotizing pancreatitis accounts for 10% of acute pancreatitis (AP) cases and is associated with a higher mortality and morbidity. Necrosis within the first 4 weeks of disease onset is defined as an acute necrotic collection (ANC), while walled ...
Christine Boumitri, Elizabeth Brown, Michel Kahaleh   +2 more
doaj   +1 more source

Efficacy of antibiotic penetration into pancreatic necrosis [PDF]

HPB, 2006
Infection of pancreatic necrosis is the most dangerous complication of acute necrotizing pancreatitis. Infection is undoubtedly caused by the endogenous flora of the host. This is why prophylaxis with a broad-spectrum antibiotic is considered an effective procedure.
Marek Krawczyk, K. Komorzycki, W. Otto
openaire   +3 more sources

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source

Imaging modalities for necrotizing pancreatitis: what’s new (literature review)

Acta Biomedica Scientifica
Pancreatic necrosis is the most severe form of acute pancreatitis; which is accompanied by a high risk of developing serious complications such as sepsis; peritonitis; multiple organ failure; etc. The mortality rate of pancreatic necrosis reaches 60–80 %;
D. V. Cherdantsev, I. G. Noskov, E. G. Takhtobin   +2 more
doaj   +1 more source

Endoscopic Transmural Necrosectomy for Walled-Off Pancreatic Necrosis: A Systematic Review and Meta-Analysis

Canadian Journal of Gastroenterology and Hepatology, 2014
BACKGROUND: Endoscopic transmural necrosectomy (ETN) is emerging as a viable treatment option for walled-off pancreatic necrosis. This NOTES-type procedure is significantly less invasive than an extensive surgical debridement; however, published data ...
Srinivas R Puli, James F Graumlich, Smitha R Pamulaparthy, Nikhil Kalva   +3 more
doaj   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Pancreatic Panniculitis in Patients with Chronic Pancreatitis: Case Report and Review of Literature

The Korean Journal of Gastroenterology, 2017
Pancreatic panniculitis is a rare complication characterized by subcutaneous fat necrosis associated with pancreatic disease. It has been postulated that pancreatic panniculitis is caused by the systemic activity of pancreatic enzymes that lead to ...
Eui Joong Kim, Min Su Chu, Ki Chang Sohn, Dong Ho Cho, Ga Hye Na, Haak Cheoul Kim, Eun Young Cho   +6 more
doaj   +1 more source