Results 41 to 50 of about 138,290 (215)
Endoscopic Ultrasound-Guided Locoregional Treatments for Solid Pancreatic Neoplasms. [PDF]
Di Gialleonardo L+7 more
europepmc +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Mechanisms of development and progression of pancreatic neoplasms. [PDF]
Furukawa T.
europepmc +1 more source
Evaluation of the effect of metal stents on dose perturbation in the carbon beam irradiation field
Abstract Propose Carbon ion therapy is indicated for cases in which stents have been inserted, such as bile ducts, but the effect of metal stents on carbon ion therapy is unclear. In this study, the dose perturbation of carbon ion therapy caused by metallic bile duct stents was evaluated by dosimetry. Materials and methods Five different types of metal
Yuya Miyasaka+8 more
wiley +1 more source
Abstract Purpose The purpose of the present study was to evaluate the impact of bone relative electron density (rED) assignment on radiotherapy planning for the abdominal region. Methods Twenty patients who received abdominal radiotherapy using MR‐Linac and underwent magnetic resonance imaging (MRI) and computed tomography (CT) simulation were analyzed.
Kota Abe+4 more
wiley +1 more source
Background features in the cytology of pancreatic neoplasms. [PDF]
Hirabayashi K, Saika T, Nakamura N.
europepmc +1 more source
Abstract Current radiotherapy practices rely on manual contouring of CT scans, which is time‐consuming, prone to variability, and requires highly trained experts. There is a need for more efficient and consistent contouring methods. This study evaluated the performance of the Varian Ethos AI auto‐contouring tool to assess its potential integration into
Robert N. Finnegan+6 more
wiley +1 more source
Abstract Purpose To assess the predictive capability of CT radiomics features for early recurrence (ER) of pancreatic ductal adenocarcinoma (PDAC). Methods Postoperative PDAC patients were retrospectively selected, all of whom had undergone preoperative CT imaging and surgery. Both patients with resectable or borderline‐resectable pancreatic cancer met
Xinze Du+7 more
wiley +1 more source