Results 51 to 60 of about 1,020,663 (289)

THE POSSIBILITIES OF ENDOSCOPIC ULTRASONOGRAPHY IN THE DIAGNOSTICS OF SOLID PANCREATIC NEOPLASMS

open access: yesКубанский научный медицинский вестник, 2018
Endosonography takes a leading role in solid pancreatic neoplasms diagnostics. This article presents the main indicators of diagnostics efficiency of the method depending on the nosology of a tumor.
N. S. Ryabin   +3 more
doaj   +1 more source

European evidence-based guidelines on pancreatic cystic neoplasms

open access: yesGut, 2018
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. This guideline is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club ...
Marco Marc Lianne Marco J Djuna L Thomas M Jeanin E Mark Del Chiaro Besselink Scholten Bruno Cahen Gress va
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Interdisciplinary Management of Cystic Neoplasms of the Pancreas

open access: yesGastroenterology Research and Practice, 2012
Cystic neoplasms of the pancreas are increasingly recognized due to the frequent use of abdominal imaging. It is reported that up to 20% of abdominal cross-sectional scans identify incidental asymptomatic pancreatic cysts.
Linda S. Lee   +4 more
doaj   +1 more source

Molecular characterization of organoids derived from pancreatic intraductal papillary mucinous neoplasms

open access: yesJournal of Pathology, 2020
Intraductal papillary mucinous neoplasms (IPMNs) are commonly identified non‐invasive cyst‐forming pancreatic neoplasms with the potential to progress into invasive pancreatic adenocarcinoma.
Bo-Nian Huang   +18 more
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Pancreatic neuroendocrine tumor with complete replacement of the pancreas by serous cystic neoplasms in a patient with von Hippel-Lindau disease: a case report

open access: yesSurgical Case Reports, 2017
Background von Hippel-Lindau disease is a dominantly inherited multi-system syndrome with neoplastic hallmarks. Pancreatic lesions associated with von Hippel-Lindau include serous cystic neoplasms, simple cysts, and neuroendocrine tumors. The combination
Shimpei Maeda   +10 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Solid Pseudopapillary Neoplasms of the Pancreas: A Report of Two Cases

open access: yesCase Reports in Medicine, 2014
Solid pseudopapillary neoplasms of the pancreas are uncommon, accounting for only 1-2% of all pancreatic neoplasms. These tumors are being detected at an increased rate, probably due to the increased awareness and the liberal use of imaging.
Dilip Dan   +4 more
doaj   +1 more source

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