Results 71 to 80 of about 576,341 (292)

Surgical Treatment of Solid Pseudopapillary Tumor in Pediatric Patients: Two Case Reports and a Brief Narrative Review

Case Reports in Oncological Medicine
Solid pseudopapillary neoplasms (SPNs) represent a tumor of the exocrine pancreas, belonging to the group of pancreatic cystic neoplasms. It is exceedingly uncommon for SPNs to manifest in extrapancreatic locations, such as the mesocolon, greater omentum,
Dario Talloa, Simona Cordaro, Giorgio Attinà, Stefano Mastrangelo, Alberto Romano, Anna Fregola, Palma Maurizi, Lorenzo Nanni, Antonio Ruggiero   +8 more
doaj   +1 more source

Clinicopathological findings of solid pseudopapillary neoplasm in a 10-year-old girl presenting with pruritus, a case report and concise review

Human Pathology: Case Reports, 2020
Solid pseudopapillary neoplasms (SPNs) are rare cystic lesions with low malignant potential making up approximately 2–3% of all primary pancreatic neoplasms in both pediatric and adult patients combined.
Sarah K. Daley, Neha Varshney, Peter Wanes, Achyut K. Bhattacharyya, Ghassan A. Tranesh   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Intraductal Papillary Mucinous Neoplasms of the Pancreas with Concurrent Pancreatic and Periampullary Neoplasms [PDF]

, 2013
Context Intraductal papillary mucinous neoplasms (IPMN) have been reported to be associated with concurrent pancreatic ductal adenocarcinoma (PDAC) in about 8% of resected branch duct lesions.
Sahora, Klaus, Warshaw, Andrew L, Crippa, Stefano, Thayer, Sarah P, Fernandez del Castillo, Carlos, Lillemoe, Keith, Partelli, Stefano, Mino-Kenudson, Mari, Ferrone, Cristina, Falconi, Massimo, Zamboni, Giuseppe   +10 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Cystic pancreatic neoplasms [PDF]

, 2015
Cystic pancreatic neoplasms are uncommon, but are being seen more frequently due to the widespread use of cross-sectional imaging. In this article, we will address the clinical and imaging features of the more commonly seen neoplasms.
Francis, Isaac R
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Driving questions and flowcharts

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
D'ONOFRIO, Mirko, DE ROBERTIS LOMBARDI, Riccardo, Martini, Paolo Tinazzi, Paolo Tinazzi Martini, CANESTRINI, Stefano, Stefano Canestrini, Crosara, Stefano, Mirko D’Onofrio, Stefano Crosara, Riccardo De Robertis   +9 more
core   +1 more source