Results 71 to 80 of about 924,048 (345)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Solid Pseudopapillary Tumor of Pancreas in a 14-year-old Adolescent Presenting With Melena: A Case Report [PDF]

Journal of Pediatrics Review, 2023
Background: The incidence of pancreatic neoplasms in infants and children is 1.8 cases per 1000000. Three of children’s most common primary pancreatic neoplasms are pancreatoblastoma, solid pseudopapillary neoplasm of the pancreas, and pancreatic ...
Fateme Fazeli, Emad Asgari Jafarabadi, Amir Hossein Zardast, Marjan Joodi, Ghodsiyeh Azarkar   +4 more
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Consensus on the clinical diagnosis and treatment of grade 3 pancreatic neuroendocrine tumors

Journal of Pancreatology
The World Health Organization (WHO) 2017 classifications for neuroendocrine neoplasms (NENs) subdivided grade 3 pancreatic neuroendocrine neoplasms (pNENs) into G3 well-differentiated pancreatic neuroendocrine tumors (G3 pNETs) and poorly differentiated ...
Jie Chen, Wenming Wu, Chunmei Bai, Yihebali Chi, Li Huo, Liming Jiang, Yuan Ji, Jie Luo, Jie Li, Jingnan Li, Wenhui Lou, Chenghao Shao, Lin Shen, Feng Wang, Yu Wang, Ling Xue, Jin Xu, Chunhui Yuan, Xianjun Yu, Xiaoyu Yin, Hong Zhao, Xiongzeng Zhu, Yupei Zhao   +22 more
doaj   +1 more source

Cytopathology of solid pancreatic neoplasms: An algorithmic approach to diagnosis

Cancer Cytopathology, 2022
Qun Wang, Michelle D. Reid
semanticscholar   +1 more source

Endoscopic ultrasound in the evaluation of pancreatic neoplasms-solid and cystic: A review.

World Journal of Gastrointestinal Endoscopy, 2015
Pancreatic neoplasms have a wide range of pathology, from pancreatic adenocarcinoma to cystic mucinous neoplasms. Endoscopic ultrasound (EUS) with or without fine needle aspiration (FNA) is a helpful diagnostic tool in the work-up of pancreatic neoplasms.
Eric M Nelsen, D. Buehler, Anurag Soni, D. Gopal   +3 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The FELIX Project: Deep Networks To Detect Pancreatic Neoplasms

medRxiv, 2022
Y. Xia, Q. Yu, L. Chu, S. Kawamoto, S. Park, F. Liu, J. Chen, Z. Zhu, B. Li, Z. Zhou, Y. Lu, Y. Wang, W. Shen, L. Xie, Y. Zhou, elliot k fishman, A. Javed, D. Fouladi, S. Shayesteh, J. Graves, A. Blanco, E. Zinreich, B. Kinny-Koster, K. Kinzler, R. Hruban, B. Vogelstein, A. Yuille, E. Fishman   +27 more
semanticscholar   +1 more source

A Clinicopathologic and Molecular Update of Pancreatic Neuroendocrine Neoplasms With a Focus on the New World Health Organization Classification.

Archives of Pathology & Laboratory Medicine, 2019
CONTEXT.— According to the 2017 World Health Organization classification, pancreatic neuroendocrine neoplasms (PanNENs) include a new category of pancreatic neuroendocrine tumor, grade 3, which is often difficult to differentiate from pancreatic ...
Jiayun M Fang, Jiaqi Shi
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source