Results 111 to 120 of about 836,777 (260)

Outcomes Following Total Pancreatectomy With and Without Vascular Resection: A NSQIP Analysis Comparing Trends in Patient Selection and Outcomes Over 5 Years

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Advances in neoadjuvant therapy and surgical techniques have led to more total pancreatectomies (TP) with vascular resection for pancreatic cancer. This study assesses contemporary outcomes of TP with venous (VR) and arterial (AR) resections compared to non‐vascular resection (NVR).
Zofia Czarnecka, Kevin Verhoeff, A. M. James Shapiro, Chaya Shwaartz   +3 more
wiley   +1 more source

CT findings of non-functioning neuroendocrine pancreatic tumors

, 2002
Neuroendocrine tumors are rare neoplasms of the pancreas, representing 0.5% of all pancreatic tumors. Approximately, one-third of neuroendocrine tumors are hormonally inactive and called non-functioning neuroendocrine tumors.
M. Secil, O. Sagol, Igci, E, A.Y. Goktay, Y. Oksuzler, E. Igci, Dicle, O, Goktay, AY, O. Dicle, SEÇİL, MUSTAFA, Oksuzler, Y, T. Pirnar, Pirnar, T, Sagol, ÖZGÜL   +13 more
core   +1 more source

Development and External Validation of a Postoperative Risk Score for Venous Thromboembolism in Epithelial Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui, Yu‐Shi He, Xuan‐Hui Wang, Cheng Li, Gang Wang, Ming Chen, Shu‐Min Chen   +6 more
wiley   +1 more source

Rare breast and subcutaneous metastases from pancreatic neuroendocrine tumor: a case report

World Journal of Surgical Oncology, 2019
Background Neuroendocrine tumors are a group of rare neoplasms, and the pancreatic neuroendocrine tumors (PNETs) represent only 1–2% of all pancreatic malignant tumors.
Dorotea Bosco, Salvatore Perrotti, Corrado Spatola, Giada Maria Vecchio, Rosalia Latino, Antonio Di Cataldo   +5 more
doaj   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Pancreatic neuroendocrine tumors: update on the new World Health Organization classification

, 2017
The first classification of the pancreatic neuroendocrine neoplasms (PanNENs) that characterized the individual tumor by criteria with prognostic significance appeared in 1995.
Capella, C., Capella C, Ohike, Nobuyuki, Scoazec JY, Osamura, Robert Y, Couvelard, A., Rindi G, La Rosa, Stefano, Klimstra, DS, Rindi, Guido, Couvelard A, Adsay, V., Hruban, RH, Couvelard, Anne, Adsay, Volkan, Perren, Aurel, Komminoth, Paul, La Rosa S, Scoazec, Jean-Yves, Hruban, Ralph H, Adsay V, Osamura, RY, Klimstra DS, Ohike N, La Rosa, S., Osamura RY, Klöppel G, Klöppel, G., Klöppel, Günter, Capella, Carlo, Perren A, Hruban RH, Klimstra, David S, Komminoth, P., Komminoth P, Ohike, N.   +35 more
core   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

NKX6-1 Is a Novel Immunohistochemical Marker for Pancreatic and Duodenal Neuroendocrine Tumors

, 2017
NKX6-1 is a homeobox transcription factor participating in the development and regulation of endocrine function of pancreatic islets. This study evaluated the potential use of NKX6-1 as a diagnostic marker for well-differentiated neuroendocrine tumors ...
Tseng, I-Ching;Yeh, Matthew M.;Yang, Ching-Yao;Jeng, Yung-Ming, 鄭永銘;楊卿堯   +1 more
core   +1 more source