Results 121 to 130 of about 22,977 (294)
Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing
Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production. ABSTRACT In the hypothalamus, detection of energy substrates such as glucose is essential to regulate ...
Sarah Geller+11 more
wiley +1 more source
The active site and mechanism of action of bovine pancreatic ribonuclease. 5. The charge types at the active centre [PDF]
Dorothy Findlay, AP Mathias, B. R. Rabin
openalex +1 more source
A CHROMATOGRAPHIC INVESTIGATION OF PANCREATIC RIBONUCLEASE [PDF]
Stanford Moore+2 more
openaire +2 more sources
ER stress amplifies TNF‐α, OSM, and IL‐1β responses in astrocytes. PERK and JAK1 signaling are required for the synergistic interaction between ER stress and inflammatory cytokines. Translational suppression attenuates the synthesis of the negative feedback regulators IκBα and SOCS3.
Anirudhya Lahiri+8 more
wiley +1 more source
On the Sequence of Residues 11 to 18 in Bovine Pancreatic Ribonuclease
Derek G. Smyth+2 more
openalex +1 more source
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li+7 more
wiley +1 more source
The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley +1 more source
The reactivity of the disulphide bonds of bovine pancreatic ribonuclease with glutathione [PDF]
BE Davidson, F.J.R. Hird
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Characterization of Sirt2 using conditional RNAi in mice [PDF]
Within the past eight years, RNA interference (RNAi) has emerged as a powerful experimental tool for gene function analysis in mice. Reversible control of shRNA mediated RNAi has been achieved by using a tetracycline (tet)-inducible promoter.
Reiss, Martina
core
The Isolation of Porcine Ribonuclease, a Glycoprotein, from Pancreatic Juice
V N Reinhold+5 more
openalex +1 more source