This study proposes an innovative therapeutic approach by combining RRM2 gene knockout with a nanocarrier system, significantly enhancing the efficacy of radiofrequency ablation for hepatocellular carcinoma. The study developed a tumor microenvironment‐responsive nanosystem that achieves synergistic effects through SPIO‐mediated and RRM2 knockout ...
Weiliang Hou+19 more
wiley +1 more source
The primary structure of goat and sheep pancreatic ribonucleases [PDF]
G.W. Welung, A.J. Scheffer, J J Beintema
openalex +1 more source
Abstract Isothermal amplification (IA) techniques have emerged as promising alternatives to polymerase chain reaction (PCR), enabling rapid and efficient nucleic acid amplification at constant temperatures. Meanwhile, clustered regularly interspaced short palindromic repeat (CRISPR)/Cas‐based technology has revolutionized molecular diagnostics by ...
Miao Liu+7 more
wiley +1 more source
Duplication and parallel evolution of the pancreatic ribonuclease gene (RNASE1) in folivorous non-colobine primates, the howler monkeys (Alouatta spp.). [PDF]
Janiak MC+3 more
europepmc +1 more source
Conformational‐transitions of bovine pancreatic ribonuclease S‐peptide
A. M. Tamburro+5 more
openalex +1 more source
Performance Evaluation of a New HRD Assay (HRDsig) in Ovarian Carcinomas in Australia
In this study we have evaluated the performance of a new HRD assay (HRDsig) against two accredited HRD assays, as well as against commercial controls and inter‐laboratory comparison samples. HRDsig has demonstrated a high concordance rate for determining HRD status in ovarian carcinomas.
Pranav Dorwal+11 more
wiley +1 more source
Reaction of Bovine Pancreatic Ribonuclease A with 1,5-Difluoro-2,4-dinitrobenzene
Peter S. Marfey+2 more
openalex +1 more source
Amino‐Acid Sequences of Red‐Deer and Roe‐Deer Pancreatic Ribonucleases [PDF]
Henk Zwiers+2 more
openalex +1 more source
Anti‐Inflammatory and Antibacterial Properties of Curcuma longa Extract Against Helicobacter pylori
This study explored the effects of Curcuma longa extract (CLE) against H. pylori infection. CLE contained 18 chemical compounds and completely inhibited growth of H. pylori Sydney strain 1 (SS1) in vitro. In infected mice with H. pylori SS1, oral administration of CLE successfully eradicated H.
Jeongsook Kim+7 more
wiley +1 more source
A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells. [PDF]
Vert A+4 more
europepmc +1 more source