Bovine pancreatic ribonuclease: fifty years of the first enzymatic reaction mechanism. [PDF]
Biochemistry, 2011 Cuchillo CM, Nogués MV, Raines RT.
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Production of ovine Pancreatic Ribonuclease and investigation of enzyme characteristics [PDF]
پژوهشهای علوم دامی ایران, 2021 Introduction Obviously, the recent decades strategy in cancer therapy, anticancer drug discovery and drug improvement is to characterize, distinguish and validate the most promising cancer-related molecular targets to which new drugs can be designed. The
mahsa Zabetian +3 more
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Ribonucleases as potential therapeutic agents [PDF]
مجله بیوتکنولوژی کشاورزی, 2021 Objective Due to high cytotoxicity effect, ribonucleases (RNases) are known as pharmacological agents with therapeutic potential. The high potential of these enzymes in the destruction of RNA strand and their other substrates and subsequently, cell ...
Masoume Vakili-Azghandi +3 more
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Biosynthesis of pancreatic ribonuclease
, 2012 Methods have been developed for the study of amino acid incorporation into a specific protein under established conditions of net synthesis. The results of these studies have been reported and discussed. Synthesis and storage of the secretory proteins of mouse pancreas have been shown to occur between fifteen to twenty-one hours after pilocarpine ...
Morris, Allan J.
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PEGylated gold nanoparticles-ribonuclease induced oxidative stress and apoptosis in colorectal cancer cells [PDF]
BioImpacts, 2020 Introduction: Currently, drug-induced reactive oxygen species (ROS) mediating apoptosis pathway have extensively been investigated in designing effective strategies for colorectal cancer (CRC) chemotherapy.
Mostafa Akbarzadeh Khiavi +7 more
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Engineering and production of recombinant bovine pancreatic ribonuclease enzyme (RNase A) as a potential therapeutic [PDF]
مجله بیوتکنولوژی کشاورزی, 2021 Objective Immunotoxins are one of the most promising ways in therapeutic fields, specially cancer therapy which have a unique toxin-antibody structure, and kill the cancer cell by passing through the cell membrane and entering the target cell.
Masoume Vakili-Azghandi +3 more
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A comparison of leaf and pancreatic ribonuclease [PDF]
Biochemical Journal, 1955 Margaret Holden, Pirie, N. W.
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Horse Pancreatic Ribonuclease [PDF]
European Journal of Biochemistry, 1974 Horse ribonuclease was purified after acid extraction of pancreas by ammonium sulfate fractionation and chromatography on CM‐cellulose. It is a glycoprotein with an average molecular weight of about 18000. The pure enzyme was chromatographically and electrophoretically heterogeneous due to the heterogeneity of the carbohydrate moiety.The amino‐acid ...
SCHEFFER, AJ, BEINTEMA, JJ
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MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy. [PDF]
PLoS ONE, 2013 Novel data showing an important role of microRNAs in mediating tumour progression opened a new field of possible molecular targets for cytotoxic ribonucleases.
Nadezhda Mironova +5 more
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