Results 211 to 220 of about 22,977 (294)

Effect of Maternal Hyperglycemia on Fetal Pancreatic Islet Development. [PDF]

open access: yesBiology (Basel)
Dias CP   +6 more
europepmc   +1 more source

RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications

open access: yesMedComm, Volume 6, Issue 8, August 2025.
RNA epigenetics regulates cancer through RNA modifications, splicing, transport, and translation. Key components include m⁶A writers, splicing factors, RBPs, and nuclear export machinery. Aberrant RNA metabolism drives tumor progression and immune evasion.
Shanhe Huang   +4 more
wiley   +1 more source

Structural Properties and Stability of Proteins in Dihydrolevoglucosenone/Water Mixtures. [PDF]

open access: yesJ Phys Chem B
Intze A   +8 more
europepmc   +1 more source

Unlocking the power of immune checkpoint inhibitors: Targeting YAP1 reduces anti‐PD1 resistance in skin cutaneous melanoma

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 16, Page 3903-3922, August 2025.
Abstract Background and Purpose Immune checkpoint inhibitors, such as anti­PD1, revolutionized melanoma treatment. However, resistance and low response rates remain problems. Our goal was to pinpoint actionable biomarkers of resistance to anti‐PD1 treatment and verify therapeutic effectiveness in vivo.
Szonja Anna Kovács   +13 more
wiley   +1 more source

Amino acid incorporation into mitochondrial ribosomes of Neurospora crassa wild-type and Mi-1 mutant [PDF]

open access: yes, 1971
Boardman, N. K.   +5 more
core   +1 more source

Dysregulated RNA m6A Methylation Contributes to the Metastasis of Gallbladder Cancer Through miR‐146a‐5p

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Gallbladder cancer (GBC) remains a challenging malignancy with a poor prognosis largely due to its highly metastatic nature and lack of effective treatment options. In this study, we investigated the role of N6‐methyladenosine (m6A) modification and its regulatory factors, METTL3 and METTL14, in GBC.
Yuhui Liu   +10 more
wiley   +1 more source

Current practice, challenges and future opportunities in the safety assessment of newly expressed proteins in genetically modified plants

open access: yesEFSA Journal, Volume 23, Issue 8, August 2025.
Abstract Current risk assessment strategies for protein safety of newly expressed proteins (NEPs) in genetically modified (GM) plants are based on chemical risk assessment principles and Codex Alimentarius guidelines for biotech‐derived foods, initially published in 2003. These guidelines were designed for proteins with multiple testing options and for
EFSA Panel on Genetically Modified Organisms (GMO)   +32 more
wiley   +1 more source

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