Results 91 to 100 of about 34,133 (252)

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Isolated pancreatic injury following blunt trauma in a child

Journal of Dr. NTR University of Health Sciences
Pancreatic injury following blunt abdominal trauma is rare (
Dicky Sherpa, Koustav Samanta, Gouranga Dutta, Pankaj Kumar Halder   +3 more
doaj   +1 more source

Indications for the surgical management of pancreatic trauma: An update. [PDF]

World J Gastrointest Surg, 2022
Pavlidis ET, Psarras K, Symeonidis NG, Geropoulos G, Pavlidis TE.   +4 more
europepmc   +1 more source

Melatonin Mitigates Doxorubicin‐Induced Cardiotoxicity by Targeting the USP18/PKM2 Axis Without Compromising Antitumor Efficacy

Advanced Science, EarlyView.
Melatonin engages MT1/MT2 receptors to suppress STAT1‐driven USP18 upregulation, thereby redirecting PKM2 ubiquitination from K33‐linked autophagic degradation toward K27‐linked nuclear translocation. This prevents PKM2‐mediated proinflammatory gene expression in the heart, alleviating doxorubicin‐induced cardiotoxicity without compromising antitumor ...
Zhenyu Feng, Yijin Yang, Jie Bai, Pengqi Sun, Xuyang Sun, Jinshu Shang, Yang Liu, Zhen Ning, Ningning Zhang, Yun‐long Xia, Yunpeng Xie   +10 more
wiley   +1 more source

Applying refined pancreaticogastrostomy techniques in pancreatic trauma. [PDF]

World J Gastrointest Surg, 2022
Krige J, Bernon M, Jonas E.
europepmc   +1 more source

The VCPIP1‐UBE3A Deubiquitination‐Ubiquitination Cascade Contributes to Castration‐Resistant Prostate Cancer Progression

Advanced Science, EarlyView.
VCIPIP1 emerges as a molecular link between protein stability and prostate cancer progression. By deubiquitinating and stabilizing UBE3A, VCIPIP1 promotes p53 degradation and progression to castration‐resistant prostate cancer. Elevated VCIPIP1 expression is associated with shorter castration‐resistant prostate cancer–free survival, highlighting the ...
Fei Lin, Wen‐Cai Zheng, Yi‐Qiu Wang, Bin Lin, Yun‐Zhi Lin, Dong‐Ning Chen, Xiao‐Dong Li, Xue‐Yi Xue, Yong Wei, Ning Xu   +9 more
wiley   +1 more source

Injectable Peptide‐Based Functional Amyloid Hydrogels as Tunable Depots for Sustained Drug Delivery

Advanced Science, EarlyView.
An injectable and tunable peptide‐based functional amyloid hydrogel provides sustained insulin release while preserving insulin stability and bioactivity. The hydrogel enables prolonged glycemic regulation in vivo, exhibits excellent biocompatibility, and shows no detectable IAPP and α‐Syn heterologous cross‐seeding, highlighting its potential as a ...
Ranjit Shaw, Niyamat M. A. Chimthanawala, Shouvik Manna, Sadhana Sathaye, Samir K. Maji   +4 more
wiley   +1 more source

Management of pancreatic trauma in urban India: A multicenter study. [PDF]

Ann Med Surg (Lond), 2022
Bavishi D, Khajanchi M, Prajapati R, Gadgil A, Sarang B, Soni KD, Banker A, Moghe D, Wärnberg MG.   +8 more
europepmc   +1 more source

Redefining the Role of Splenectomy in Scirrhous Gastric Cancer: Toward a Selective Multimodal Strategy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Scirrhous gastric cancer, characterized by diffuse infiltration and a high propensity for peritoneal dissemination, remains one of the most aggressive subtypes of gastric cancer. Despite a relatively high incidence of splenic hilar lymph node (No. 10) metastasis, the oncologic benefit of splenectomy remains controversial, while its association
Tsutomu Hayashi, Takaki Yoshikawa
wiley   +1 more source

Celiac pseudoaneurysm rupture after ligation in the setting of a pancreatic fistula following penetrating trauma

Journal of Vascular Surgery Cases and Innovative Techniques
Trauma to the celiac artery may require ligation as a life-saving maneuver. Our patient sustained a gunshot wound resulting in celiac artery ligation during trauma laparotomy. Abdominal closure occurred the following day with drains placed owing to grade
Brett J. Salomon, MD, Ryan Z. Taylor, MD, Reagan W. Bollig, MD, Michael B. Freeman, MD, Lauren B. Grimsley, MD   +4 more
doaj   +1 more source