Results 21 to 30 of about 57,090 (266)

Pandemic preparedness and cooperative justice [PDF]

Developing World Bioethics, 2020
AbstractBy examining the global public good nature of pandemic preparedness we can identify key social justice issues that need to be confronted to increase citizens’ voluntary compliance with prevention and mitigation measures. As people tend to cooperate on a voluntary basis only with systems they consider fair, it becomes difficult to ensure ...
openaire   +3 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Efficacy of baloxavir marboxil against bovine H5N1 virus in mice

Nature Communications
Since the first detection of highly pathogenic avian influenza (HPAI) H5N1 (clade 2.3.4.4b) in U.S. dairy cattle in early 2024, the virus has spread rapidly, posing a major public health concern as the number of human cases continues to rise.
Maki Kiso, Ryuta Uraki, Seiya Yamayoshi, Yoshihiro Kawaoka   +3 more
doaj   +1 more source

Mental health consequences of COVID-19: a nationally representative cross-sectional study of pandemic-related stressors and anxiety disorders in the USA

BMJ Open, 2021
Objective To document the prevalence of anxiety disorders in the USA during the COVID-19 pandemic.Design A cross-sectional analysis.Setting A nationally representative sample in the USA between 31 March and 13 April 2020.Participants 1450 English ...
Sandro Galea, Salma M Abdalla, Catherine K Ettman, Gregory H Cohen   +3 more
doaj   +1 more source

Pandemic Preparedness: The Importance of Adequate Immune Fitness

Journal of Clinical Medicine, 2022
Pandemic preparedness is an important issue in relation to future pandemics. The two studies described here aimed to identify factors predicting the presence and severity of coronavirus disease 2019 (COVID-19) symptoms. The CLOFIT study comprised an online survey among the Dutch population (n = 1415). Perceived immune fitness before the pandemic (2019)
Pantea Kiani, Jessica Balikji, Aletta D. Kraneveld, Johan Garssen, Gillian Bruce, Joris C. Verster   +5 more
openaire   +5 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Informing social media analysis for public health: a cross-sectional survey of professionals

Archives of Public Health
Background During the COVID-19 pandemic, the field of infodemic management has grown in response to urgent global need. Social listening is the first step in managing the infodemic, and many organizations and health systems have implemented processes ...
Becky K. White, Elisabeth Wilhelm, Atsuyoshi Ishizumi, Surangani Abeyesekera, Alhassan Pereira, Brian Yau, Aleksandra Kuzmanovic, Tim Nguyen, Sylvie Briand, Tina D. Purnat   +9 more
doaj   +1 more source

The pathogenesis of zoonotic viral infections: Lessons learned by studying reservoir hosts

Frontiers in Microbiology, 2023
Zoonotic viral infections that cause severe disease or even death in some people may be asymptomatic or mild in reservoir hosts. Comparison of the pathogenesis of these two host categories may potentially explain the difference in disease.
Lineke Begeman, Debby van Riel, Marion P. G. Koopmans, Marion P. G. Koopmans, Thijs Kuiken   +4 more
doaj   +1 more source

Longitudinal Changes in Adiposity after a Youth Sport‐Related Knee Injury: Informing Post‐Traumatic Osteoarthritis Prevention

Arthritis Care &Research, Accepted Article.
Objective Youth who experience a sport‐related knee injury have elevated odds of overweight or obesity in 3‐10 years, compounding their risk for post‐traumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth in the 2‐year period ...
Justin M. Losciale, Nuria EJ Jansen, Christina Y. Le, Leo Lu, Hui Xie, Marienke van Middelkoop, Jackie L. Whittaker   +6 more
wiley   +1 more source

The Cost of a Nutritious Diet in Cafeterias: Evidence From US Military Dining Facilities

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Providing nutritious meals in institutional settings with financial constraints, such as military dining facilities, is challenging. The US Department of War (DoW) and US Department of Agriculture (USDA) collaborated to modernize the Basic Daily Food Allowance (BDFA) using an optimization model that incorporates service members' consumption ...
Linlin Fan, Yiwen Zhao, Andrea Carlson, Parke Wilde, Joanna Reagan, Julianna Jayne, Starr Seip, Denise Laursen, Matthew P. Rabbitt   +8 more
wiley   +1 more source