Results 41 to 50 of about 1,068,976 (306)

Barriers and drivers influencing people's behaviour towards COVID-19 public health and social measures in the Netherlands

Public Health in Practice
Background: The disease burden of COVID-19 infection, morbidity, and mortality was unevenly distributed across different population subgroups. A one-size-fits-all approach may not reach all groups.
Valérie Eijrond, Nora Bünemann, Nicky Renna, Brett Craig, Katrine Bach Habersaat, Hélène Voeten, Pearl Dykstra, Anja Schreijer   +7 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

A rapid evaluation of the preparedness of Ethiopia's disease surveillance system for Mpox outbreak: a cross-sectional study of perspectives from professionals across various levels

Tropical Medicine and Health
Background The potential re-emergence of Mpox poses an increasing public health concern in the Horn of Africa, particularly in Ethiopia. This study examined perceptions of preparedness among surveyed surveillance professionals in Ethiopia regarding the ...
Gelan Ayana Zewdie, Henok Gulilat, Ketema Lemma Abdi, Firanol Teshome, Gelane Biru, Hundessa Daba Nemomssa, Tabarak Malik, Million Tesfaye Eshete, Mirkuzie Woldie, Ahmed Zeynudin, Adane Tadesse Gebryu, Netsanet Workneh Gidi, Minyahil Tadesse Boltena, Jude Kong   +13 more
doaj   +1 more source

Estimating the effect of South Africa travel restrictions in November 2021 on the SARS-CoV-2 Omicron outbreak in the Netherlands: a descriptive analysis and modelling study

BMJ Open
Background Governments used travel bans during the COVID-19 pandemic to limit the introduction of new variant of concern (VoC). In the Netherlands, direct flights from South Africa were banned from 26 November 2021 onwards to curb Omicron (B.1.1.529 ...
Roisin Bavalia, Elke Wynberg, Sherman Lee, Valerie Eijrond, Luc E Coffeng, Anne de Vries, Saskia van Egmond, Lobke Brals, Noud A J Schel, Lotte Harbers, Bas Kolen, Sake De Vlas, Anja Schreijer   +12 more
doaj   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Risk factors associated with the intensity of COVID-19 outbreaks in Canadian community settings: a retrospective analysis of outbreak-level surveillance data

BMC Public Health
Background The severity of COVID-19 outbreaks is disproportionate across settings (e.g., long-term care facilities (LTCF), schools) across Canada. Few studies have examined factors associated with outbreak severity to inform prevention and response.
Demy Dam, Michelle Chen, Erin E. Rees, Bethany Cheng, Lynn Sukkarieh, Erin McGill, Yasmina Tehami, Anna Bellos, Jonathan Edwin, Kaitlin Patterson   +9 more
doaj   +1 more source

Pandemic preparedness and cooperative justice [PDF]

Developing World Bioethics, 2020
AbstractBy examining the global public good nature of pandemic preparedness we can identify key social justice issues that need to be confronted to increase citizens’ voluntary compliance with prevention and mitigation measures. As people tend to cooperate on a voluntary basis only with systems they consider fair, it becomes difficult to ensure ...
openaire   +3 more sources

Extreme Weather Events and Consumer Food Responses

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study investigates consumer food responses to Hurricanes Helene and Milton, which affected a swath of the Southeastern U.S. in 2024. Using representative consumer survey data from six affected states, we analyze 10 distinct food responses classified into ex ante and ex post responses, and examine their associations with food insufficiency
Ahmad Zia Wahdat, Joseph Balagtas
wiley   +1 more source

The pathogenesis of zoonotic viral infections: Lessons learned by studying reservoir hosts

Frontiers in Microbiology, 2023
Zoonotic viral infections that cause severe disease or even death in some people may be asymptomatic or mild in reservoir hosts. Comparison of the pathogenesis of these two host categories may potentially explain the difference in disease.
Lineke Begeman, Debby van Riel, Marion P. G. Koopmans, Marion P. G. Koopmans, Thijs Kuiken   +4 more
doaj   +1 more source

Influenza and the implications of a pandemic for Malta [PDF]

, 2005
An influenza pandemic is inevitable and recent reports from Southeast Asia on avian influenza viruses infecting humans have served to fuel worries that a new pandemic is near.
Melillo Fenech, Tanya, Farrugia, Ryan, Spiteri, Gianfranco   +2 more
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