Results 71 to 80 of about 318,454 (302)

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Defusing COVID-19: Lessons Learned from a Century of Pandemics

open access: yesTropical Medicine and Infectious Disease, 2020
Amidst the COVID-19 global pandemic of 2020, identifying and applying lessons learned from previous influenza and coronavirus pandemics may offer important insight into its interruption.
Graciela Mujica   +6 more
doaj   +1 more source

Ancient Yersinia pestis genomes from across Western Europe reveal early diversification during the First Pandemic (541–750)

open access: yes, 2019
The first historically documented pandemic caused by Yersinia pestis began as the Justinianic Plague in 541 within the Roman Empire and continued as the so-called First Pandemic until 750.
Bates, J.   +25 more
core   +1 more source

Distribution of selected healthcare resources for influenza pandemic response in Cambodia. [PDF]

open access: yes, 2013
INTRODUCTION: Human influenza infection poses a serious public health threat in Cambodia, a country at risk for the emergence and spread of novel influenza viruses with pandemic potential.
Borin, Khieu   +7 more
core   +3 more sources

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

Application of a Sensitive Capture Sequencing Approach to Reservoir Surveillance Detects Novel Viruses in Zambian Wild Rodents

open access: yesViruses
We utilized a pan-viral capture sequencing assay, VirCapSeq-VERT, to assess viral diversity in rodents from the Eastern Province of Zambia as a model for pre-pandemic viral reservoir surveillance.
Lavel C. Moonga   +12 more
doaj   +1 more source

Entropy-Based Pandemics Forecasting

open access: yesFrontiers in Physics, 2020
A great variety of natural phenomena follows some statistical distributions. In epidemiology, such as for the current COVID 19 outbreak, it is essential to develop reliable predictions of the evolution of an infectious disease.
Umberto Lucia   +2 more
doaj   +1 more source

The association of physical function with psychosocial patient‐reported outcomes in people with systemic lupus erythematosus

open access: yesArthritis Care &Research, Accepted Article.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts [Approaches to Positive, Patient‐centered Experiences of Aging with Lupus (APPEAL) and California Lupus Epidemiology Study
Mrinalini Dey   +8 more
wiley   +1 more source

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