Results 51 to 60 of about 1,254,937 (311)
Sociological Science, 2023 Sociological research is increasingly using survey panel data to examine changes in diverse outcomes over life course events. Most of these studies have one striking similarity: they analyze changes between yearly time intervals.
Ansgar Hudde, Marita Jacob
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Panel Smooth Transition Regression Models [PDF]
We develop a non-dynamic panel smooth transition regression model with fixed individual effects. The model is useful for describing heterogenous panels, with regression coefficients that vary across individuals and over time. Heterogeneity is allowed for
Andres Gonzalez +2 more
core +3 more sources
Journal of Management and Entrepreneurship Research, 2020 Objective: Indonesia’s economic growth is mostly supported by the agricultural sector in which the plantation sub-sector has a significant contribution to the primary sector in the sectoral index of Indonesia Stock Exchange (IDX).
Siska Gita Pratiwi
doaj +1 more source
Exploration of Spatio-Temporal Evolution and Threshold Effect of Shrinking Cities
Land, 2023 Shrinking cities are a global issue with regional characteristics. This paper focuses on the county-level administrative units in the Three Northeastern Provinces in China to identify and classify shrinking cities using a two-step identification method ...
Yuanzhen Song, Weijie He, Jian Zeng
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Frontiers in Energy Research, 2023 Chinese heavy-polluting companies have been facing enormous challenges in responding to climate risk and energy transformation. This paper uses panel regression model and investigates the impact of climate risk on corporate green innovation in Chinese ...
Shixian Ling, Hongfu Gao
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Firm growth dynamics in Iranian insurance industry [PDF]
پژوهشهای اقتصادی, 2013 Traditional approach to the firm size and its growth rate is based on comparative statics analysis and it does not really deal with the dynamics of growth.
Ahmad Sadraei Javaheri
doaj