Results 21 to 30 of about 4,564 (171)

TPST2-mediated receptor tyrosine sulfation enhances leukocidin cytotoxicity and S. aureus infection

Frontiers in Immunology, 2023
BackgroundAn essential fact underlying the severity of Staphylococcus aureus (S. aureus) infection is the bicomponent leukocidins released by the pathogen to target and lyse host phagocytes through specific binding cell membrane receptors.
Jie He, Xianggui Yang, Kai Yang, Honglin Xu, Cheng Chen, Junxiong Wang, Jun Zeng   +6 more
doaj   +1 more source

Spontaneous tibiotalar arthrodesis as a complication of acute tibial osteomyelitis due to Panton-Valentine leukocidin-producing Staphylococcus aureus: a case report

Journal of Medical Case Reports, 2012
Introduction Strains of Panton-Valentine leukocidin-producing Staphylococcus aureus producing a new pattern of disease have emerged worldwide. Infection with these bacteria typically presents as a life-threatening infection of soft tissues and bones, and
Ceroni Dimitri, de la Llana Rebecca, Zand Tristan, Lamah Léopold, Dominguez Denis, De Coulon Geraldo, Dubois-Ferrière Victor   +6 more
doaj   +1 more source

Methicillin sensitive Staphylococcus aureus producing Panton-Valentine leukocidin toxin in Trinidad & Tobago: a case report

Journal of Medical Case Reports, 2011
Introduction Certain Staphylococcus aureus strains produce Panton-Valentine leukocidin, a toxin that lyses white blood cells causing extensive tissue necrosis and chronic, recurrent or severe infection.
Rao AV, Swanston William H, Monecke Stefan, Akpaka Patrick E, Schulz Renee, Levett Paul N   +5 more
doaj   +1 more source

Bacteremic necrotizing mediastinitis caused by community-associated clonal complex 398 methicillin-resistant Staphylococcus aureus in a baby aged 4 months

International Journal of Infectious Diseases, 2023
Invasive community-associated methicillin-resistant Staphylococcus aureus (MRSA) diseases caused by clonal complex 398 MRSA without animal contact have become a new emerging threat.
Chun Yi Lee, Chih Jung Chen
doaj   +1 more source

Molecular Typing of Methicillin Resistant Staphylococcus aureus using coa Gene Polymerase Chain Reaction-Restriction Fragment Length Polymorphism: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Methicillin Resistant Staphylococcus aureus (MRSA) are the most important multidrug resistant pathogen of humans causing a wide array of infections.
P Hema, B Appalaraju, R Someshwaran
doaj   +1 more source

Success stories about severe pneumonia caused by Panton–Valentine leucocidin-producing Staphylococcus aureus

Brazilian Journal of Infectious Diseases, 2014
We describe three cases of community-acquired necrotizing pneumonia which were caused by Panton–Valentine leucocidin-producing strains of Staphylococcus aureus (one of them methicillin sensitive).
Paramythiotou Elisabeth, Souli Maria, Galani Irene, Giamarellou Helen, Armaganidis Apostolos   +4 more
doaj   +1 more source

The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors [PDF]

Cell Host & Microbe, 2013
Panton-Valentine Leukocidin (PVL) is a staphylococcal bicomponent pore-forming toxin linked to severe invasive infections. Target-cell and species specificity of PVL are poorly understood, and the mechanism of action of this toxin in Staphylococcus aureus virulence is controversial. Here, we identify the human complement receptors C5aR and C5L2 as host
Spaan, András N, Henry, Thomas, van Rooijen, Willemien J M, Perret, Magali, Badiou, Cédric, Aerts, Piet C, Kemmink, Johan, de Haas, Carla J C, van Kessel, Kok P M, Vandenesch, François, Lina, Gérard, van Strijp, Jos a G   +11 more
openaire   +3 more sources

Panton-Valentine Leukocidin-Positive Staphylococcus aureus Infections in Returning Travelers [PDF]

The American Society of Tropical Medicine and Hygiene, 2010
Skin and soft tissue infections caused by Panton-Valentine leukocidin-producing strains of Staphylococcus aureus are emerging among travelers returning from the tropics. Here, we here present data on 15 affected individuals. Intrafamiliar spread was documented in one case, and occupational transmission was assumed in another.
Dennis, Tappe, Marco H, Schulze, Anett, Oesterlein, Doris, Turnwald, Andreas, Müller, Ulrich, Vogel, August, Stich   +6 more
openaire   +2 more sources

Remitting infections due to community-acquired Panton–Valentine leukocidin-producing Staphylococcus aureus in the Milan area

Journal of Infection and Public Health, 2018
One of the most important Staphylococcus aureus virulence factors is Panton–Valentine leukocidin (PVL). We describe an outbreak of recurrent cutaneous PVL infections in different members of three family clusters.
Sara G. Rimoldi, Cristina Pagani, Erika Longhi, Valentina D. Cristo, Annamaria D. Gregorio, Alessandro Mancon, Pietro Zerbi, Cristina Gervasoni, Maria R. Gismondo, Agostino Riva   +9 more
doaj   +1 more source

Two Different Panton-Valentine Leukocidin Phage Lineages Predominate in Japan [PDF]

Journal of Clinical Microbiology, 2008
ABSTRACT We determined the entire nucleotide sequence of φSa2958-carrying Panton-Valentine leukocidin (PVL) gene, which was lysogenized in a sequence type 5 staphylococcal cassette chromosome mec (SCC mec ) type II strain of methicillin-resistant Staphylococcus aureus
Xiao Xue, Ma, Teruyo, Ito, Yoko, Kondo, Moe, Cho, Yukio, Yoshizawa, Jun, Kaneko, Atsuo, Katai, Masato, Higashiide, Shanshuang, Li, Keiichi, Hiramatsu   +9 more
openaire   +2 more sources