Results 51 to 60 of about 4,564 (171)

Inhibitory Effect of Amentoflavone on the Virulence of MRSA by Targeting ClpP

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Methicillin‐resistant Staphylococcus aureus (MRSA) poses significant therapeutic challenges due to its global spread and virulence. Targeting the critical virulence regulator ClpP presents a promising antivirulence strategy. This study investigated AMF's mechanism against MRSA through molecular dynamics simulations, FRET and TSA.
Teri Gele, Xiangri Kong, Qiuyue Zhang, Wu Song, Junpeng Guo, Paizati Hamidi, Kulishasi Mani, Shaoyu Han, Xuan Zhao, Jingwen Chen, Chi Zhang, Abduldayeva Aigul Abduldayevna, Qingjie Li   +12 more
wiley   +1 more source

Antibiotic Resistance, Biofilm Formation, and Molecular Epidemiology of Foodborne Staphylococcus aureus Isolated in Northwest Hubei Province, China

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
This study reveals a high prevalence of foodborne S. aureus in northwest Hubei Province, with MRSA strains displaying significantly elevated antibiotic resistance and biofilm‐forming capacities compared to MSSA strains. The high carriage rates of enterotoxin genes across isolates underscore the potential of these strains to contribute to foodborne ...
Yitong Tang, Yanyan Li, Na Xiao, Lu Wang, Shichao Li, JiuMing Zou, Yanmin Yu, Jinhui Shao, Ming Jiang   +8 more
wiley   +1 more source

A φSa3int (NM3) Prophage Domestication in Staphylococcus aureus Leads to Increased Virulence Through Human Immune Evasion

MedComm, Volume 6, Issue 8, August 2025.
Prophages play a significant role in modulating bacterial virulence and pathogenicity. Our results suggest domestication of φSa3int prophage leads to reduced phagocytosis mediating escape of S. aureus from human innate immunity. As such, targeted identification of mobile genetic elements (MGEs) in addition to species and strain identification may lead ...
Roshan Nepal, Ghais Houtak, George Bouras, Sholeh Feizi, Gohar Shaghayegh, Keith Shearwin, Mahnaz Ramezanpour, Alkis James Psaltis, Peter‐John Wormald, Sarah Vreugde   +9 more
wiley   +1 more source

Staphylococcus aureus Causing Tropical Pyomyositis, Amazon Basin, Peru

Emerging Infectious Diseases, 2013
We studied 12 Staphylococcus aureus isolates causing tropical pyomyositis in the Amazon Basin of Peru. All isolates were methicillin-susceptible; 11 carried Panton-Valentine leukocidin–encoding genes, and 5 belonged to multilocus sequence type 25 and ...
Coralith García, Marie Hallin, Ariane Deplano, Olivier Denis, Moises Sihuincha, Rozanne de Groot, Eduardo Gotuzzo, Jan Jacobs   +7 more
doaj   +1 more source

Investigating the Prevalence of Enterotoxin and Antibiotic Resistance in Methicillin‐Resistant Staphylococcus aureus (MRSA) Isolated From Meat and Edible Viscera of Broiler Chickens

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
The results indicated high prevalence of MRSA in broilers, which is very worrying issue. It was observed that due to the increase in the use of antibiotics in poultry farming, bacteria resistant to methicillin and other antibiotics have a high prevalence.
Mousavi Bideli Seyedeh Mozhgan, Rahimi Ebrahim, Seyed Majid Hashemi, Zia Jahromi Noosha   +3 more
wiley   +1 more source

Staphylococcus aureus From Prosthetic Joint Infections and Blood Cultures Display the Same Genetic Background

APMIS, Volume 133, Issue 7, July 2025.
ABSTRACT Hematogenous prosthetic joint infections (PJIs) are primarily associated with Staphylococcus aureus, and there is a 30%–40% risk of contracting a hematogenous PJI following an S. aureus bacteremia. The aim of this study was to investigate whether identical strains of S. aureus were present in each patient from a cohort with both bacteremia and
Bo Söderquist, Peter Wildeman, Marc Stegger, Bianca Stenmark   +3 more
wiley   +1 more source

Panton-Valentine leukocidin in pediatric community-acquired Staphylococcus aureus infections

Clinical and Investigative Medicine, 2009
Purpose Panton-Valentine Leukocidin (PVL) is an exotoxin produced by strains of Staphylococcus aureus (SA). Its importance as a virulence factor is controversial. We aim to further characterize the role of PVL in pediatric community-acquired SA infections.
Jesse, Papenburg, Patricia, Fontela, Lélia, Raynal, Louise, Jetté, Johanne, Ismail, Sadjia, Bekal, Ibrahim, Al-Zahrani, Caroline, Quach   +7 more
openaire   +3 more sources

Identification of staphylococcal Panton-Valentine leukocidin as a potent dermonecrotic toxin [PDF]

Infection and Immunity, 1980
The Panton-Valentine leukocidin of Staphylococcus aureus was shown to exhibit a potent dermonecrotic effect when injected intradermally into rabbits. This effect could be abrogated by immunizing animals with the F component or both components, but immunization with the S component appeared to exacerbate certain of the intradermal responses.
P D, Ward, W H, Turner
openaire   +2 more sources

The Host Adaptation of Staphylococcus aureus to Farmed Ruminants in New Zealand, With Special Reference to Clonal Complex 1

Environmental Microbiology Reports, Volume 17, Issue 3, June 2025.
ABSTRACT Genetic features of host adaptation of S. aureus to ruminants have been extensively studied, but the extent to which this adaptation occurs in nature remains unknown. In New Zealand, clonal complex 1 (CC1) is among the most common lineages in humans and the dominant lineage in cattle, enabling between‐, and within‐CC genomic comparisons of ...
Jabin Nesaraj, Alex Grinberg, Richard Laven, Ryan Chanyi, Eric Altermann, Claudio Bandi, Patrick J. Biggs   +6 more
wiley   +1 more source

Prevalence and Risk Factors of Staphylococcus aureus Nasal Colonization in Horses Admitted to a Veterinary Teaching Hospital

Journal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.
ABSTRACT Background Methicillin‐resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infections, including in veterinary settings. Hypothesis/Objectives To investigate the prevalence, risk factors for Staphylococcus aureus (SA) and MRSA colonization, and the duration of MRSA colonization.
Marion Allano, Julie Arsenault, Marie Archambault, Julie‐Hélène Fairbrother, Frédéric Sauvé   +4 more
wiley   +1 more source