Results 51 to 60 of about 4,774 (150)

Panton-Valentine Leukocidin in the Pathogenesis of Community-associated Methicillin-resistant Staphylococcus aureus Infection

Pediatrics and Neonatology, 2011
Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that causes serious infectious diseases and was endemic in hospitals by the late 1960s.
Wen-Tsung Lo, Chih-Chien Wang
doaj   +1 more source

Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity

Toxins, 2020
Staphylococcal bi-component pore-forming toxins, also known as leukocidins, target and lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins Panton-Valentine leukocidin (PVL), γ-haemolysin AB (HlgAB) and CB (HlgCB ...
Angelino T. Tromp, Michiel Van Gent, Joris P. Jansen, Lisette M. Scheepmaker, Anneroos Velthuizen, Carla J.C. De Haas, Kok P.M. Van Kessel, Bart W. Bardoel, Michael Boettcher, Michael T. McManus, Jos A.G. Van Strijp, Robert Jan Lebbink, Pieter-Jan A. Haas, András N. Spaan   +13 more
doaj   +1 more source

Development and usage of protein microarrays for the quantitative measurement of Panton-Valentine leukocidin

Molecular and Cellular Probes, 2014
Staphylococcus aureus is a human pathogen that can harbour several genes encoding exotoxins including leukocidins. A clinically most relevant factor is Panton-Valentine leukocidin (PVL) because of its association with chronic, recurrent or severe skin and soft tissue infections.
Stieber, B., Monecke, S., Mϋller, E., Baier, V., Coombs, Geoffrey, Ehricht, R.   +5 more
openaire   +3 more sources

Disseminated Panton-Valentine Leukocidin-Positive Staphylococcus aureus infection in a child

Archivos Argentinos de Pediatria, 2016
Panton-Valentine leukocidin (PVL) is an exotoxin that is produced by many strains of Staphylococcus aureus, and an important virulence factor. A PVL-positive S. aureus infection leads to rapid and severe infections of soft tissue and necrotizing pneumonia in healthy adolescents, and has a high mortality.
Arzu, Karli, Keramettin, Yanik, Muhammet S, Paksu, Gulnar, Sensoy, Alper, Aykanat, Nazik, Yener, Nursen, Belet, Meltem, Ceyhan   +7 more
openaire   +2 more sources

Comparison of USA300 with non-USA300 methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit

International Journal of Infectious Diseases, 2019
Objectives: Reports of USA300 methicillin-resistant Staphylococcus aureus (MRSA) strain were still scarce in neonatal intensive care units (NICUs) and the relationship of USA300 MRSA to clinical infections is still controversial.
Takemi Murai, Kaoru Okazaki, Kazue Kinoshita, Yuki Uehara, Hui Zuo, Yujie Lu, Yuki Ono, Takashi Sasaki, Keiichi Hiramatsu, Yuho Horikoshi   +9 more
doaj   +1 more source

Healthcare-associated transmission of Panton-Valentine leucocidin positive methicillin-resistant Staphylococcus aureus: the value of screening asymptomatic healthcare workers

BMC Infectious Diseases, 2018
Background Three patients hospitalised in the coronary care unit of a general district hospital (England, UK) were tested positive for Panton-Valentine leucocidin methicillin-resistant Staphylococcus aureus colonisation during their routine weekly ...
Panagiotis Papastergiou, Eleni Tsiouli
doaj   +1 more source

Severe infections of Panton-Valentine leukocidin positive Staphylococcus aureus in children

Medicine, 2019
Abstract Infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus (PVL-SA) mostly present as recurrent skin abscesses and furunculosis. However, life-threatening infections (eg, necrotizing pneumonia, necrotizing fasciitis,
Hoppe, Pia-Alice, Holzhauer, Susanne, Lala, Birgit, Bührer, Christoph, Gratopp, Alexander, Hanitsch, Leif Gunnar, Humme, Daniel, Kieslich, Moritz, Kallinich, Tilmann, Lau, Susanne, Leistner, Rasmus, Niebank, Michaela, Pokrywka, Anna, Ringe, Hannelore, Schaper, Anne-Sophie, Schröder, Jennyver-Tabea, Schwarz, Carsten, Staab, Doris, Stegemann, Miriam Songa, Thee, Stephanie, Varnholt, Verena, von Bernuth, Horst, Weber-Carstens, Steffen, Wendt, Anke, Krüger, Renate   +24 more
openaire   +2 more sources

Spread of Tst–Positive Staphylococcus aureus Strains Belonging to ST30 Clone among Patients and Healthcare Workers in Two Intensive Care Units

Toxins, 2017
Staphylococcus aureus is a major cause of infections. Toxic shock syndrome toxin (TSST-1) and Panton–Valentine leukocidin (PVL) are associated with severe clinical syndromes. S. aureus colonizing isolates recovered from healthcare workers and patients in
Matthaios Papadimitriou-Olivgeris, Eleanna Drougka, Fotini Fligou, Vasiliki Dodou, Fevronia Kolonitsiou, Kriton S. Filos, Evangelos D. Anastassiou, Efthimia Petinaki, Markos Marangos, Iris Spiliopoulou   +9 more
doaj   +1 more source

Severe invasive methicillin-resistant S. aureus (USA300 clone) infection in an Italian adolescent

Clinical Management Issues, 2009
This report describes an uncommon presentation of invasive community-acquired methicillin-resistant S. aureus (CA-MRSA) infection in an immunocompetent adolescent without any other risk factor, characterized by septicaemia, meningitis, necrotising ...
Piero Valentini, Donatella Angelone, Francesca Crea, Annalisa Pantosti   +3 more
doaj   +1 more source

Detection of Panton-valentine Leukocidin Gene Isoforms of Staphylococcus aureus Isolates in Al-Zahra Hospital, Isfahan-Iran

Advanced Biomedical Research, 2017
Background: Panton-Valentine leukocidin (PVL) is a gamma-toxin produced by Staphylococcus aureus encoded by genes lukS/lukF-PV with several single-nucleotide polymorphisms. A mutation at nucleotide position 527 results in substitution of histidine (H) to
Seyed Asghar Havaei, Farkhondeh Poursina, Maryam Ahmadpour, Seyed Roholla Havaei, Meisam Ruzbahani   +4 more
doaj   +1 more source