Results 11 to 20 of about 9,574 (196)

Comparative transcriptome analysis using high papaverine mutant of Papaver somniferum reveals pathway and uncharacterized steps of papaverine biosynthesis. [PDF]

open access: yesPLoS ONE, 2013
The benzylisoquinoline alkaloid papaverine, synthesized in low amount in most of the opium poppy varieties of Papaver somniferum, is used as a vasodilator muscle relaxant and antispasmodic.
Sumya Pathak   +6 more
doaj   +2 more sources

Local Effects of Papaverine on Normal, Atherosclerotic, and Vasospastic Carotid Arteries of Rabbits: An Experimental Study [PDF]

open access: yesBagcilar Medical Bulletin, 2017
Objective: Papaverine is a direct-acting vasodilating agent that is frequently used in the treatment of vasospasm after subarachnoid hemorrhage. However, not much knowledge is available about the effect of papaverine on atherosclerotic vessels.Material ...
Azmi Tufan   +4 more
doaj   +2 more sources

Reaction of Papaverine with Baran DiversinatesTM

open access: yesMolecules, 2019
The reaction of papaverine with a series of Baran DiversinatesTM is reported. Although the yields were low, it was possible to synthesize a small biodiscovery library using this plant alkaloid as a scaffold for late-stage C−H functionalization. Ten
Folake A. Egbewande   +3 more
doaj   +2 more sources

THE SULFONATION STUDY OF REACTION MECHANISM ON PAPAVERINE ALKALOID BY GC-MS AND FT-IR [PDF]

open access: yesIndonesian Journal of Chemistry, 2010
The aim of this research was to prove theoretical mechanism reaction on the sulfonation of papaverine alkaloid and the result could be used as a reference on the transformation of these alkaloid to the other derivatives.
I Made Sudarma
doaj   +2 more sources

Anticancer effects of a non-narcotic opium alkaloid medicine, papaverine, in human glioblastoma cells.

open access: yesPLoS ONE, 2019
The interaction between high-mobility group box 1 protein (HMGB1) and receptor for advanced glycation end products (RAGE) is important for tumor cell growth. We investigated the tumor biological effects of HMGB1 and RAGE interaction.
Mana Inada   +7 more
doaj   +2 more sources

The protective effect of Papaverine and Alprostadil in rat testes after ischemia and reperfusion injury [PDF]

open access: yesInternational Brazilian Journal of Urology, 2018
Objective: To investigate the effect of papaverine and alprostadil on testicular torsion-detorsion injury in rats. Materials and Methods: A total of 40 male Wistar-Albino rats were used in this study.
Mehmet Ali Karagoz   +7 more
doaj   +2 more sources

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

open access: yesArchaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares   +5 more
wiley   +1 more source

Papaverine and hepatotoxicity [PDF]

open access: yesPostgraduate Medical Journal, 1980
Abstract Six of 14 patients receiving a sustained release papaverine preparation developed abnormal liver function tests. One patient had jaundice and another abnormal liver histology on a biopsy specimen. This is only the third report of impaired liver function following the administration of papaverine--a drug which has been used in ...
M S, Pathy, A J, Reynolds
openaire   +2 more sources

Papaverinol-N-Oxide: A Microbial Biotransformation Product of Papaverine with Potential Antidiabetic and Antiobesity Activity Unveiled with In Silico Screening

open access: yesMolecules, 2023
Bioconversion of biosynthetic heterocyclic compounds has been utilized to produce new semisynthetic pharmaceuticals and study the metabolites of bioactive drugs used systemically.
Duaa Eliwa   +8 more
doaj   +1 more source

Quantitative estimation of LIMA blood flow between extraluminal papavarine vs extraluminal papavarine plus intraluminal vasodilator cocktail in CABG patients

open access: yesAnnals of Cardiac Anaesthesia, 2020
Objective: In this study, we aimed at a comparative quantitative estimation of the difference in LIMA blood flow between LIMAs treated with topical papaverine alone and LIMAs treated with a combination of topical papaverine plus an intraluminal cocktail ...
Vivek V Pillai   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy