Results 41 to 50 of about 9,574 (196)

Vasodilatory Efficacy and Impact of Papaverine on Endothelium in Radial Artery Predilatation for CABG Surgery: in Search for Optimal Concentration

Brazilian Journal of Cardiovascular Surgery
Objective: The aim of this study was to compare the efficacy of two different papaverine concentrations (0.5 mg/ml and 2 mg/ml) for vasospasm prevention and their impact on endothelium integrity.
Piotr Węgrzyn, Grzegorz Lis, Paweł Rudzinski, Jacek Piatek, Grazyna Pyka-Fosciak, Ryszard Korbut, Boguslaw Kapelak, Krzysztof Bartus, Radoslaw Litwinowicz   +8 more
doaj   +1 more source

Effect of local papaverine on arteriovenous fistula maturation in patients with end-stage renal disease

Brazilian Journal of Nephrology, 2019
Background: Arteriovenous fistula (AVF) maturation is one of the main concerns in patients with end-stage renal disease (ESRD) and finding a strategy for increasing success rate and accelerating fistula maturation is valuable.
Reza Manani, Gholamreza Kazemzadeh, Ali Saberi, Fatemeh Sadeghipour, Asghar Rahmani   +4 more
doaj   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, Volume 15, Issue 31, 21 August 2026.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source

Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care

Catheterization and Cardiovascular Interventions, Volume 108, Issue 2, Page 287-300, August 1, 2026.
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn, Matthew A. Soderstrom, Ariana Ramirez, John‐Henry Dean, Raj Shah, Debanshu Roy, Kenneth Stone, Ariel Vinas, Bryan Ramsey, Charles Lin, Robert Chilton   +10 more
wiley   +1 more source

Vorinostat Mitigates Early Brain Injury Following Subarachnoid Hemorrhage Through Modulation of the C3aR1/TGF‐β/Smad Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
C3aR1 mediates microglial activation after SAH in part through the TGF‐β/Smad signaling pathway. Vorinostat alleviates early brain injury after SAH by reducing C3aR1 levels. ABSTRACT Background Excessive microglial activation after subarachnoid hemorrhage (SAH) contributes to early brain injury (EBI) and poor clinical outcomes.
Chonghui Zhang, Yifan Xu, Junshan Wan, Jinpeng Wu, Chao Wang, Yugong Feng   +5 more
wiley   +1 more source

Chronic Spontaneous Coronary Artery Dissection in a Young Woman Managed With Coronary Artery Bypass Grafting: A Case Report With Literature Review

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Spontaneous coronary artery dissection (SCAD) is an uncommon, non‐atherosclerotic cause of acute coronary syndrome, typically occurring in young to middle‐aged women. Although most cases resolve spontaneously with conservative therapy, a small proportion develop chronic dissections that require revascularization.
Gashaw Solela, Desalew Mekonnen, Nish Patel, Jim Kauten, Chala Fekadu Oljira, Adane Petros, Siraj Kemal Mussa, Gashayeneh Genetu Tiruneh, Getu Kusa Wakoya, Tesfamariam Aklilu Betemariam, Dagmawit Mesfin Tasew, Clifford J. Kavinsky, Tesfaye Telila, Obsinet Merid   +13 more
wiley   +1 more source

Conditional knockout of membrane‐type I matrix metalloproteinase in smooth muscle cells of adult mice alleviates atherosclerosis without affecting basic cardiovascular function

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Expression of smooth muscle cell‐specific MMP14 increases with atherosclerosis progression in humans. Inducible conditional knockout of SMC‐MMP14 in adult mice does not affect cardiac or vascular function. Inducible conditional knockout of SMC‐MMP14 in adult Ldlr−/− mice decreases atherosclerosis progression, increases plaque stability and accelerates ...
Suha Jarad, Hong‐Mei Gu, Daniel Huang, Peter Amadi, Govind Gill, Floor Spaans, Aakar Chatha, Ala Yousef, Murilo E. Graton, Raj Patel, John M. Seubert, Ying Wang, Gordon Francis, Xiao‐Dan Xia, Sandra T. Davidge, Da‐Wei Zhang   +15 more
wiley   +1 more source

Intracisternal papaverine toxicity in anterior circulation aneurysm clipping surgery: A literature review

, 2020
Introduction. Cerebral vasospasm is a major cause of mortality in patients with subarachnoid haemorrhage. Irrigation of intracisternal papaverine has been adopted as a strategy to reduce the incidence of aneurysm-surgery-associated vasospasm.
Al-Sharshahi, Zahraa F., Almurayati, Mustafa E., Hoz, Samer S., Ameen, Zahraa, Kareem, Zahraa M.   +4 more
core   +1 more source

Effects of parenteral papaverine and piracetam administration on cochlea following acoustic trauma

Noise and Health, 2018
Introduction: Noise exposure, the main cause of hearing loss in countries with lot of industries, may result both in temporary or permanent hearing loss.
Nurcan Yurtsever Kum, Yavuz F Yilmaz, Seren G Gurgen, Rauf O Kum, Muge Ozcan, Adnan Unal   +5 more
doaj   +1 more source

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

Food Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun, Daoyan Xiao, Xingyue Li, Zhaofei Wang, Maoqin Xia, Chao Song, Hong‐Lei Li   +6 more
wiley   +1 more source