Results 21 to 30 of about 9,574 (196)
Phosphodiesterase type 10A inhibitor attenuates lung fibrosis by targeting myofibroblast activation
iScience, 2023 Summary: Pulmonary fibrosis (PF) is a fatal and irreversible respiratory disease accompanied by excessive fibroblast activation. Previous studies have suggested that cAMP signaling pathway and cGMP-PKG signaling pathway are continuously down-regulated in
Ya-Jun Li +8 more
doaj +1 more source
Papaverine Prevents Vasospasm by Regulation of Myosin Light Chain Phosphorylation and Actin Polymerization in Human Saphenous Vein. [PDF]
PLoS ONE, 2016 OBJECTIVE:Papaverine is used to prevent vasospasm in human saphenous veins (HSV) during vein graft preparation prior to implantation as a bypass conduit.
Kyle M Hocking +5 more
doaj +1 more source
Indian Journal of Urology, 2021 Drug-induced priapism is well known and papaverine is the most common drug known to cause priapism. Drotaverine, an analog of papaverine, is used extensively to treat Colicky pain. We report the first case of drotaverine.induced priapism.
Ajay Shyam Kanbur +2 more
doaj +1 more source
Simplified Assessment of the Index of Microvascular Resistance
Journal of Interventional Cardiology, 2021 Background. To validate a simplified invasive method for the calculation of the index of microvascular resistance (IMR). Methods. This is a prospective, single-center study of patients with chronic coronary syndromes presenting with nonobstructive ...
Monika Kodeboina +15 more
doaj +1 more source
Mid-term results of autoinjection therapy for erectile dysfunction [PDF]
, 1988 Of over 300 patients with erectile dysfunction, 186 were selected for intracavernosal autoinjection therapy with a standardized papaverine-phentolamine mixture.
Stief, Christian Georg +3 more
core +1 more source
Interdisciplinary Neurosurgery, 2019 Background and objective: Papaverine hydrochloride is a direct-acting vasodilator used to manage vasospasm during various neurosurgical operations. Transient hearing loss due to vasospasm of Internal auditory artery during Posterior Fossa Microvascular ...
Carlo Giacobbo Scavo, MD +4 more
doaj +1 more source
Translational Research in Urology, 2021 Introduction: For erectile dysfunction (ED) treatment, Vacuum therapy (VT) utilizes negative pressure to distend the corporal sinusoids and to increase the blood inflow to the penis. In the current study, we evaluated the vacuum constrictive device (VCD)
Amir Ghasemlouei +4 more
doaj +1 more source
Non-Classical Effects of the cAMP Accumulation Activators In Vivo [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: Wound-healing dipyridamole- and papaverine-based aerosols (D1/D2) as activators of the accumulation of cyclic adenosine monophosphate are promising drugs that can accelerate wound healing in wound processes of various origins.
Artur Martynov +4 more
doaj +1 more source