Results 81 to 90 of about 26,987,137 (296)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Promise of Evidence-Based Policymaking: Report of the Commission on Evidence-Based Policymaking, Appendices E-H

, 2017
Final report appendices E-H of the Commission on Evidence-Based Policymaking (CEP) containing the information gathered through the commission's survey of federal offices, public meeting materials and presentations, public input-hearing testimony and ...
United States. Commission on Evidence-Based Policymaking
core  

Poly(ionic liquid) functionalization: A general strategy for strong, tough, ionic conductive, and multifunctional polysaccharide hydrogels toward sensors

SusMat
Ionic conductive hydrogels (ICHs) prepared from natural bioresources are promising candidates for constructing flexible electronics for both commercialization and environmental sustainability due to their intrinsic characteristics.
Xue Yao, Sufeng Zhang, Ning Wei, Liwei Qian, Hao Ding, Jingtao Liu, Wenqi Song, Sergiu Coseri   +7 more
doaj   +1 more source

Paper-based pump-free magnetophoresis

Analytical Methods, 2020
Microfluidic magnetophoresis is a powerful technique that is used to separate and/or isolate cells of interest from complex matrices for analysis.
Zachary D. Call, Cody S. Carrell, Ilhoon Jang, Brian J. Geiss, David S. Dandy, Charles S. Henry   +5 more
openaire   +3 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The Promise of Evidence-Based Policymaking: Appendices E-H

, 2017
Supplementary appendices that support the final report of the Commission on Evidence-Based Policymaking including ..
United States. Commission on Evidence-Based Policymaking.
core  

Paper for printed electronics and functionality [PDF]

, 2013
Mass-produced paper electronics (large area organic printed electronics on paper-based substrates, “throw-away electronics”) has the potential to introduce the use of flexible electronic applications in everyday life.
Bollström, Roger
core  

Opportunities and Challenges of Biomass-based Electromagnetic Shielding Materials

BioResources
Biomass with its abundance, renewability, and processability has been extensively studied and utilized for developing electromagnetic interference (EMI) shielding materials as an alternative to non-renewable metal-based EMI shielding materials.
Jinlong Zhang, Shiyu Fu
doaj  

A Dual‐Phase Pore Engineering Strategy to Enhance Low‐Voltage Plateau Capacity of Hard Carbon for Sodium‐Ion Batteries

Carbon Energy
Hard carbon is the most commercially viable anode material for sodium‐ion batteries (SIBs), and yet, its practical implementation remains constrained by insufficient low‐voltage plateau capacity, a critical parameter governing storage capacity.
Wei Zhao, Shuai Zhang, Haihong Lai, Wenxiu He, Boon Kar Yap, Usisipho Feleni, Xinwen Peng, Jinlong Cui, Linxin Zhong   +8 more
doaj   +1 more source

Paper-Based Nanoplatforms for Multifunctional Applications

Journal of Nanomaterials, 2019
In this work, zinc oxide (ZnO) and titanium dioxide (TiO2) nanostructures were grown on different cellulose paper substrates, namely, Whatman, office, and commercial hospital papers, using a hydrothermal method assisted by microwave irradiation.
M. L. Matias, D. Nunes, A. Pimentel, S. H. Ferreira, R. Borda d’Agua, M. P. Duarte, E. Fortunato, R. Martins   +7 more
openaire   +2 more sources