Results 61 to 70 of about 100,553 (269)
Paper-based analytical devices for smart foodborne pathogen detection
Talanta OpenFood safety continues to be a critical global challenge, with foodborne pathogens posing significant risks to public health and economic stability. The rapid detection of these pathogens, especially in resource-limited settings, is essential to mitigate ...
Hadeer M. Bedair +6 more
doaj +1 more source
Paper-based smart microfluidics for education and low-cost diagnostics
South African Journal of Science, 2015 Current centralised healthcare models pose many challenges, particularly for developing countries such as South Africa, where travel and time costs make it difficult for patients to seek healthcare, even when urgently needed. To address this issue, point-
Suzanne Smith +12 more
doaj +1 more source
Electrochemistry Communications, 2020 Laser-scribed electrochemical paper-based devices (LS-ePADs) are emerging as a greener alternative to conventional carbon electrochemical sensors since their fabrication does not involve the use of chemicals and the resulting devices show good ...
Nikola Tasić +7 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Printed platforms for paper-based analytical applications [PDF]
, 2014 Paper-based analytical technologies enable quantitative and rapid analysis of analytes from various application areas including healthcare, environmental monitoring and food safety.
Määttänen, Anni
core
Molecules, 2021 Proteinuria is a condition in which an excessive amount of protein is excreted in urine. It is, among others, an indicator of kidney disease or risk of cardiovascular disease.
Izabela Lewińska +2 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Micromachines, 2016 General biochemistry detection on paper-based microanalytical devices (PADs) uses pipette titration. However, such an approach is extremely time-consuming for large-scale detection processes.
Hsiang-Li Wang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Simultaneous colorimetric detection of improvised explosive compounds using microfluidic paper-based analytical devices (μPADs) [PDF]
, 2015 © 2014 The Royal Society of Chemistry. In this paper the development of microfluidic paper-based analytical devices (μPADs) is described for rapid, on-site detection of improvised explosives.
Zreibe, K +5 more
core +1 more source