Results 71 to 80 of about 39,332,435 (296)

LED&Paper-based analytical device for phosphatemia/calcemia diagnostics☆

Journal of Pharmaceutical and Biomedical Analysis, 2020
In this communication a prototype of paper-based analytical device designed for simultaneous determination of orthophosphate and calcium ions, which levels are significant for hyperphosphatemia diagnostics, is presented. The laboratory-on-paper structure for two analytes detection was wax-printed on the surface of filter paper.
Marta Fiedoruk-Pogrebniak, Robert Koncki
openaire   +3 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

An Extended CMOS ISFET Model Incorporating the Physical Design Geometry and the Effects on Performance and Offset Variation [PDF]

, 2011
17/04/13 meb. Accepted version OK to pub.This paper presents an extended model for the CMOS-based Ion-Sensitive-Field-Effect-Transistor (ISFET), incorporating design parameters associated with the physical geometry of the device.
Liu, Y, Georgiou, Pantelis, Pantelis Georgiou, Timothy G. Constandinou, Prodromakis, T, Constandinou, TG, Georgiou, P, Themistoklis Prodromakis, Prodromakis, Themistoklis, Toumazou, Christofer, Liu, Yan, Yan Liu, Christofer Toumazou, Constandinou, Timothy G, Toumazou, C   +14 more
core   +1 more source

Application of Paper-Based Microfluidic Analytical Devices (μPAD) in Forensic and Clinical Toxicology: A Review [PDF]

, 2023
The need for providing rapid and, possibly, on-the-spot analytical results in the case of intoxication has prompted researchers to develop rapid, sensitive, and cost-effective methods and analytical devices suitable for use in nonspecialized laboratories
Dossi, Nicolò, Bortolotti, Federica, Grazioli, Cristian, Tagliaro, Franco, Stefano Fornasaro, Fornasaro, Stefano, Elio Franco De Palo, De Palo, Elio Franco, Giacomo Musile, Nicolò Dossi, Franco Tagliaro, Musile, Giacomo, Cristian Grazioli, Federica Bortolotti   +13 more
core   +1 more source

Graphene-supported Pd/Pt nano-catalysts for enhanced colorimetric detection of dopamine and NADH using paper-based microfluidic devices

ADMET and DMPK
Background and purpose: Dopamine and nicotinamide adenine dinucleotide (NADH) are key biomarkers associated with neurological and metabolic disorders.
Ruri Wahyuono, Jovin Jovin, Ignacius Gilbert Chano, Arda Fridua Putra, Annisa Septyana Ningrum, Muhammad Yusuf Hakim Widianto, Irkham Irkham, Yeni Wahyuni Hartati, Wulan Tri Wahyuni, Isnaini Rahmawati, Chi-Hsien Huang, Yi-Ting Lai   +11 more
doaj   +1 more source

Fully Enclosed Microfluidic Paper-Based Analytical Devices

, 2016
This article introduces fully enclosed microfluidic paper-based analytical devices (microPADs) fabricated by printing toner on the top and bottom of the devices using a laser printer. Enclosing paper-based microfluidic channels protects the channels from
Jason A. Kurian (2116279), Kevin M. Schilling (2116282), Anna L. Lepore (2116285), Andres W. Martinez (2101561)   +3 more
core   +1 more source

Advancement in Paper-Based Electrochemical Biosensing and Emerging Diagnostic Methods

, 2023
The utilization of electrochemical detection techniques in paper-based analytical devices (PADs) has revolutionized point-of-care (POC) testing, enabling the precise and discerning measurement of a diverse array of (bio)chemical analytes. The application
Stephen Benjamin, Reinaldo Oriá, Fábio de Lima, Geanne de Andrade, Valter Nascimento   +4 more
core   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Development of Paper-Based Analytical Devices for Minimizing the Viscosity Effect in Human Saliva

, 2018
Rationale: Saliva as a sample matrix is rapidly gaining interest for disease diagnosis and point-of-care assays because it is easy to collect (non-invasive) and contains many health-related biomarkers.
Noiphung, Julaluk, Henry, Charles S, Punyadeera, Chamindie, Nguyen, Michael P, Wan, Yunxia, Laiwattanapaisal, Wanida   +5 more
core   +1 more source