Results 61 to 70 of about 686,721 (344)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Novel design of low volume mobile phase paper chromatography

Green Analytical Chemistry
A novel design and set up of paper chromatography in the form of radial serpentine arms laying horizontally is proposed. The consumption of mobile phase is reduced to be 1 mL or less as compared to the tens of mL typically used in the conventional set ...
Jacob DeMott, Zachary Hilvano, Hunter Cann, Isa Baldwin-Zurek, William Kershisnik, Supaporn Kradtap Hartwell   +5 more
doaj   +1 more source

Genipin cross-linked chitosan for signal enhancement in the colorimetric detection of aflatoxin B1 on 3MM chromatography paper

Sensing and Bio-Sensing Research, 2020
Detection of mycotoxins by conventional methods such as ELISA or LC-MS can be expensive and time-consuming. Therefore, paper-based biosensors can be effectively used for on-site analysis, due to their low cost and easy detection procedures. Nevertheless,
V.A. Mirón-Mérida, M. Wu, Y.Y. Gong, Y. Guo, M. Holmes, R. Ettelaie, F.M. Goycoolea   +6 more
doaj   +1 more source

Bioassay-guided isolation and identification of antimicrobial compounds from thyme essential oil by means of overpressured layer chromatography, bioautography and GC-MS [PDF]

, 2012
A simple method is described for efficient isolation of compounds having an antibacterial effect. Two thyme (Thymus vulgaris) essential oils, obtained from the market, were chosen as prospective materials likely to feature several bioactive components ...
Andrea Böszörményi, B Lorber, BJ Juven, C Anagnostopoulos, C Rota, E Mincsovics, E Mincsovics, E Mincsovics, E Wedge, Emil Mincsovics, EO King, Ernő Tyihák, Gy Horváth, IM Choma, J Fan, L Botz, PZ Wang, Péter G. Ott, RR Nelson, S Koduru, Ágnes M. Móricz, ÁM Móricz, ÁM Móricz, Éva Lemberkovics   +23 more
core   +1 more source

Highly Sensitive Electrochemical Biosensor Based on Hairy Particles with Controllable High Enzyme Loading and Activity

Advanced Functional Materials, EarlyView.
For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin, Anila Antony, Hongtao Cai, Antonia Debevc, Ceyda Topal, Anne Linhardt, Alla Synytska, Leonid Ionov   +7 more
wiley   +1 more source

Plant pigments (antioxidants) of medicinal plants Malva Sylvestris l. and Malva Moschata l. (Malvaceae)

Biomolecules & Biomedicine, 2005
Qualitative-quantitative structure of plant pigments in wild plants Malva silvestrs L. and Malva moschata L. (Malvaceae), which were collected in 20 locations in Sarajevo area and surroundings, was tested during spring and summer in 2003.
Sulejman Redžić, Nizama Hodžić, Mijat Tuka   +2 more
doaj   +1 more source

Extraction Methods and an Investigation of Drosophila Lipids [PDF]

, 1959
In earlier work (8) we extracted lipids from dried, macerated Drosophila melanogaster with ether, but later, working with larger quantities of undried flies, we found that most of the phospholipids were autolyzed.
Mitchell, Herschel K., Wren, J. J.
core  

Effects of antibodies against tubulin on the movement of reactivated sea urchin sperm flagella [PDF]

, 1980
Antibodies binding to sea urchin flagellar outer-doublet tubulin have been isolated from rabbit sera by tubulin-affinity chromatography employing electrophoretically purified tubulin as the immobilized substrate.
Asai, David J., Brokaw, Charles J.
core   +1 more source

Pore Size Effects of Mesoporous N‐Doped Carbon Nanospheres as Advanced Support Material on the Activity of Molybdenum Sulfide Catalysts for the Hydrogen Evolution Reaction

Advanced Functional Materials, EarlyView.
By tuning the pore size of mesoporous N‐doped carbon (MPNC) nanospheres as support material for molybdenum sulfide, the electrochemical activity of the composite material for the hydrogen evolution reaction can be optimized. An ideal MPNC pore size of 60 nm allows a high number of molybdenum sulfide active sites while maintaining efficient proton and ...
Niklas Ortlieb, Christian Völker, Lars Guggolz, Anna Fischer   +3 more
wiley   +1 more source

Determination of Radiochemical Purity of 99mTc-DTPA Using One-System Method of Paper Chromatography [PDF]

Journal of Pure and Applied Chemistry Research, 2019
The more efficient and effective quality control techniques for 99mTc-DTPA are needed because 99mTc has a short half-life of around 6.0 hours. We have succeeded in developing a one-system of TLC for radiochemical purity testing system that is faster and ...
Maskur Maskur, Enny Lestari, Amal Rezka Putra, Dede Kurniasih, Endang Sarmini, Yayan Tahyan, Adang Hardi Gunawan, Arni Aries   +7 more
doaj