Results 71 to 80 of about 521,053 (283)

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Analysis of water-soluble vitamins in biopharma raw materials by electrophoresis micro-chips with contactless conductivity detection [PDF]

, 2009
Detailed information concerning the composition of the raw materials employed in the production of biologics is important for the efficient control and optimization of bioprocesses.
Benito-Lopez, Fernando, Diamond, Dermot, Garcia-Cordero, Jose L., Vázquez, Mercedes   +3 more
core  

Optimizing end-labeled free-solution electrophoresis by increasing the hydrodynamic friction of the drag-tag

, 2009
We study the electrophoretic separation of polyelectrolytes of varying lengths by means of end-labeled free-solution electrophoresis (ELFSE). A coarse-grained molecular dynamics simulation model, using full electrostatic interactions and a mesoscopic ...
Ahlrichs P., Cottet H., Deserno M., Desruisseaux C., Dünweg B., Dünweg B., Grass K., Grass K., Grosser S. T., Haynes R. D., Heller C., Hoagland D. A., Hsiao P.-Y., Hu S., Kan C. W., Limbach H. J., Lobaskin V., Lobaskin V., Lobaskin V., Long D., Manning G. S., McCormick L. C., McCormick L. C., McCormick L. C., McCormick L. C., McNamara G. R., Meagher R. J., Meagher R. J., Mohanty U., Muthukumar M., Nedelcu S., Nedelcu S., Ren H., Savard J. M., Savard J. M., Slater G. W., Soddemann T., Stellwagen E., Ullner M., Viovy J. L., Volkel A. R., Vreeland W. N., Weeks J. D., Wolff U.   +43 more
core   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Determination of mixed stability constants of lead(II)/uranyl(II)-NTA-cysteine complexes by paper electrophoresis

Bulletin of the Chemical Society of Ethiopia, 2005
A method involving the use of paper ionophoresis is described for the study of equilibria in mixed – ligand complex systems in solution. The technique is based on the movement of a spot of metal ion under an electric field with the complexants added to ...
Brij Bhushan Tewari
doaj  

Analysis of proteins from marine molluscs [PDF]

, 2009
Application of the two-dimensional gel electrophoresis (2DE) protocols which were developed for samples of mammalian origin gives unsatisfactory results when used in samples from marine molluscs. This chapter describes a detailed protocol of 2DE that can
Bebianno, Maria João, Chora, Suze, Roméo, Michèle   +2 more
core   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source

Temperature and denaturing substances influence on Lab-on-a-chip electrophoresis [PDF]

Journal of Medical Biochemistry, 2009
Qualitative and quantitative determination of proteins in different biological fluids is of great significance in medicine, due to their importance in diagnosis and treatment of some diseases.
Trenčevska Olgica, Aleksovski Vasko, Stojanoski Kiro   +2 more
doaj  

Capillary electrophoresis characterisation of a rapid prototyped PMMA chip for particle analysis [PDF]

, 2010
Màster en Nanociència i NanotecnologiaA rapid and cheap method has been developed for the fabrication of a capillary electrophoresis chip for the preliminary characterization of particles.
Colom, Adai
core   +1 more source

Brownian Dynamics Studies on DNA Gel Electrophoresis. II. `Defect' Dynamics in the Elongation-Contraction Motion

, 2001
By means of the Brownian dynamics (BD) method of simulations we have developed, we study dynamics of individual DNA undergoing constant field gel electrophoresis (CFGE), focusing on the relevance of the `defect' concept due to de Gennes in CFGE.
Azuma, Ryuzo
core   +1 more source