Results 41 to 50 of about 25,243 (199)

Metachronous Follicular Variant of Papillary Thyroid Microcarcinoma in a Case of Medullary Carcinoma Thyroid [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2016
Medullary carcinoma and papillary thyroid carcinoma arise from the different cells. Simultaneous occurrence of both types is rare. Medullary carcinomas are characterised by calcitonin positivity.
Neelam Sood, Binit Kumar Khandelia
doaj  

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

open access: yesAdvanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang   +8 more
wiley   +1 more source

Axillary chest wall solid-papillary carcinoma: A case report on presentation and management

open access: yesRare Tumors, 2023
Papillary breast carcinomas comprise
Harper E. Niver DO   +1 more
doaj   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Solid papillary breast carcinoma arising in the male axilla: A case report

open access: yesCurrent Problems in Cancer: Case Reports, 2020
Solid papillary carcinoma is a rare type of breast cancer, with an estimated incidence of 1% of all breast cancer cases. In this case report, a 64 year old male presented with a painless axillary mass.
Vaishali Purohit   +3 more
doaj   +1 more source

SV2B Promotes the Progression of TFE3‐Rearranged Renal Cell Carcinoma by Interacting with HERC2 to Impede the Degradation of NF‐κB Subunits

open access: yesAdvanced Science, EarlyView.
TFE3‐rearranged renal cell carcinoma (TFE3‐RCC) lacks clearly defined diagnostic and therapeutic targets. SV2B, a TFE3 target gene, promotes TFE3‐RCC progression by activating the NF‐κB pathway. Targeted inhibition with padsevonil or Withaferin A effectively suppresses tumor progression.
Huayi Feng   +13 more
wiley   +1 more source

A five-gene signature predicts overall survival of patients with papillary renal cell carcinoma.

open access: yesPLoS ONE, 2019
BACKGROUND:The present study aims to investigate the gene expression changes in papillary renal cell carcinoma(pRCC) and screen several genes and associated pathways of papillary renal cell carcinoma progression.
Ze Gao   +6 more
doaj   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

open access: yesAdvanced Science, EarlyView.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu   +20 more
wiley   +1 more source

Hypopharyngeal and Parapharyngeal Space Metastasis of Papillary Thyroid Carcinoma: A Case Report

open access: yesBalkan Medical Journal, 2014
Background: Carcinoma of the thyroid gland is one of the most commonly encountered endocrine malignancies. Papillary carcinoma is the most common histological type, and its spread is usually lymphatic.
Aysegul Batıoğlu Karaaltın   +4 more
doaj   +1 more source

Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning

open access: yesAdvanced Science, EarlyView.
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou   +27 more
wiley   +1 more source

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