Results 61 to 70 of about 307,949 (334)
Minimally invasive papillary carcinoma of the extrahepatic bile ducts [PDF]
, 2008 Invasive papillary carcinomas of the Extrahepatic Bile Ducts (EBD) are uncommon (4-5%). The course is less aggressive than conventional adenocarcinomas of the extrahepatic bile ducts.
Ahmad, Zubair +4 more
core +1 more source
A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC [PDF]
, 2015 The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor mediating the toxicity and tumor-promoting properties of dioxin. AHR has been reported to be overexpressed and constitutively active in a variety of solid tumors, but few data
Barollo, Susi +16 more
core +4 more sources
Advanced Science, EarlyView.Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang +16 more
wiley +1 more source
Investigating the association of rs2910164 with cancer predisposition in an Irish cohort. [PDF]
, 2017 IntroductionMicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA).
Bell, M +11 more
core +3 more sources
Papillary Thyroid Carcinoma and Inflammation [PDF]
Frontiers in Endocrinology, 2011 The relationship between cancer and inflammation is well known since 1863 when Rudolf Virchow, following the observation of leukocytes in neoplastic tissues, hypothesized that chronic inflammation could contribute to the tumorigenic process. In the following decades, several lines of evidence suggested a strong association between chronic inflammation ...
L. Fugazzola +3 more
openaire +3 more sources
Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D
Advanced Science, EarlyView.CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley +1 more source
BMC Urology, 2013 Background Papillary renal cell carcinoma is a rare cancer. Some cases can be attributed to individuals with hereditary renal cell carcinomas usually consisting of the clear cell subtype.
Behnes Carl Ludwig +7 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.Anti‐inflammatory drugs may be effective in improving recurrence‐free survival after radical gastrectomy in patients with pStage II or III gastric cancer. ABSTRACT Background Elevated postoperative inflammation is associated with reduced recurrence‐free survival (RFS) after gastrectomy in patients with gastric cancer, independent of postoperative ...
Ryota Matsui +7 more
wiley +1 more source
Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]
, 2017 Background: Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Blandamura, Stella +6 more
core +2 more sources
Annals of Gastroenterological Surgery, EarlyView.We assessed the prognostic ability of the Immunoscore and PD‐L1 or PD‐L2 expression in pStage III GC patients by immunohistochemistry. The results showed that Immunoscore was an independent prognostic factor in differentiated GC, but not in undifferentiated GC.
Yoshiro Yukawa +13 more
wiley +1 more source