Results 51 to 60 of about 41,781 (278)

Comparison of neutrophil–lymphocyte ratio and platelet–lymphocyte ratio in patients with thyroiditis and papillary tumors

Journal of International Medical Research, 2019
Objective The neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) have recently been introduced as prognostic markers of thyroid cancer and strong inflammatory markers.
Aziz Ari, Feray Gunver
doaj   +1 more source

HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer [PDF]

, 2015
High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm and extra-cellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system ...
ANTONACI, Alfredo, FAGGIONI, Alberto, Fico, F., MARDENTE, Stefania, MARI, EMANUELA, MASSIMI, ISABELLA, PULCINELLI, FABIO MARIA, ZICARI, Alessandra   +7 more
core   +4 more sources

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

Case report: Lymph node metastases of breast cancer and thyroid cancer encountered in axilla

Frontiers in Oncology, 2022
Occurrences of breast cancer and thyroid cancer metachronously or synchronously are common for women, but axillary lymph node metastasis from both cancers is rarely seen.
Rihan Li, Rihan Li, Qingfu Zhang, Dongdong Feng, Dongdong Feng, Feng Jin, Siyuan Han, Siyuan Han, Xinmiao Yu, Xinmiao Yu   +9 more
doaj   +1 more source

Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]

, 2018
There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin, Alecu, Lucian, Cristian, Balalau, Hainarosie, Razvan, Jecan, Radu, Nitipir, Cornelia, Orlov, Cristina, Pantea Stoian, Anca, Pituru, Silviu, Poiana, Catalina, Slavu, Iulian, Tomescu, Luminita, Tulin, Raluca   +12 more
core   +1 more source

Coexistence of papillary thyroid cancer with Hashimoto thyroiditis [PDF]

Langenbeck's Archives of Surgery, 2012
Conflicting data have been reported with regard to Hashimoto thyroiditis (HT) and risk of malignancy. The aim of this study was to evaluate coexistence of papillary thyroid cancer (PTC) with HT.This is a retrospective cohort study in which HT was diagnosed in 452 (F/M ratio = 405:47, median age 53.5 ± 12.1 years) of 7,545 patients qualified for ...
Konturek, Aleksander, Barczyński, Marcin, Wierzchowski, Wojciech, Stopa, Małgorzata, Nowak, Wojciech   +4 more
openaire   +4 more sources

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Remarkable response to alectinib for metastatic papillary thyroid cancer with STRN-ALK fusion: A case report

Frontiers in Oncology, 2022
Little is known about the efficacy of alectinib for papillary thyroid cancer with STRN-ALK fusion. A 64-year-old female presented with metastatic papillary thyroid cancer, widespread to lungs, mediastinal lymph nodes and brain 20 years after surgery ...
Lucheng Zhu, Lucheng Zhu, Shenglin Ma, Bing Xia, Bing Xia   +4 more
doaj   +1 more source

Extracellular Superoxide Dismutase Expression in Papillary Thyroid Cancer Mesenchymal Stem/Stromal Cells Modulates Cancer Cell Growth and Migration [PDF]

, 2017
Tumor stroma-secreted growth factors, cytokines, and reactive oxygen species (ROS) influence tumor development from early stages to the metastasis phase.
Cantu, D., CAPPELLO, Francesco, Castellone, M., Chen, H., Hematti, P., Kim, J., Laukkanen, M., Mazzoccoli, G., Parascandolo, A., RAPPA, Francesca, Salvatore, M.   +10 more
core   +1 more source

Iodine nutrition and papillary thyroid cancer

Frontiers in Nutrition, 2022
Thyroid cancer (TC) is the most frequent endocrine malignancy. The incidence of TC, especially papillary thyroid carcinoma (PTC), has continued to rise all over the world during the past few years, for reasons that are not entirely clear. Though the phenomenon of overdiagnosis is occurring, it is not the sole driver of the substantial increase in ...
Xueqi Zhang, Fan Zhang, Qiuxian Li, Chuyao Feng, Weiping Teng   +4 more
openaire   +3 more sources