Results 51 to 60 of about 19,247 (199)
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
A Case of Multiple Sclerosis Presenting as Eight and Half Syndrome. [PDF]
Multiple sclerosis (MS) is a chronic disease characterized by inflammation, demyelination, gliosis (scarring), and neuronal loss; the course can be relapsing-remitting or progressive.
Kaushik, M +4 more
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Unilateral optic neuropathy following subdural hematoma: a case report [PDF]
Introduction Unilateral optic neuropathy is commonly due to a prechiasmatic affliction of the anterior visual pathway, while losses in visual hemifields result from the damage to brain hemispheres.
Alexandra Kretz +22 more
core +1 more source
A Case of Knobloch Syndrome With Lens Dislocation Resembling Homocystinuria
ABSTRACT We report a 39‐year‐old woman with lifelong visual impairment who presented in June 2024 with progressive visual deterioration in her right eye. Ophthalmologic evaluation revealed severe high myopia, vitreoretinal degeneration, phthisis bulbi of the left eye, and downward lens dislocation of the right eye.
Elnaz Asadollahzadeh +4 more
wiley +1 more source
ABSTRACT Moyamoya syndrome (MMS) is a rare progressive cerebrovascular disorder causing stenosis of intracranial arteries and collateral vessel formation. Pediatric presentations often include ischemic strokes, and coexisting Thalassemia Major may worsen vascular outcomes.
Kshitiz Parajuli +8 more
wiley +1 more source
Unilateral Papilledema with Bilateral Optic Nerve Sheath Distension: A Case Report
Bilateral edematous optic disc swelling from papilledema is caused by elevated intracranial pressure (ICP). Idiopathic intracranial hypertension (IIH), a clinical syndrome with elevated ICP of unclear etiology, is a frequent cause of this condition.
Raghda Shawky El-Gendy +4 more
doaj +1 more source
Papilledema is one of the causes of reduction or loss of visual acuity. Fora better understanding of this abnormality,the nor- mal anatomy of the optic disk is briefly described followed by the possible causes of papilledema and the changes observed ...
Soeroso, Admadi
core
Elevated cerebral spinal fluid biomarkers in children with mucopolysaccharidosis I-H. [PDF]
Mucopolysaccharidosis (MPS) type-IH is a lysosomal storage disease that results from mutations in the IDUA gene causing the accumulation of glycosaminoglycans (GAGs).
Dickson, Patricia I +6 more
core +1 more source
Glymphatic System Dysfunction in Central Nervous System Diseases
Glymphatic Dysfunction in Neurological Disorders: The glymphatic system is a brain‐wide clearance system that removes neurotoxic waste via AQP4‐mediated CSF‐ISF exchange. Dysfunction through AQP4 mislocalization, BBB injury, and inflammation annihilates clearance and causes acute (stroke, TBI) and chronic disease.
Anwar Zahran +14 more
wiley +1 more source
The diagnostic challenge of evaluating papilledema in the pediatric patient
Pseudopapilledema is a fairly common finding in ophthalmic practice, and in many cases, the diagnosis is straightforward. However, an accurate diagnosis can challenge the most seasoned clinicians, and missing true papilledema can result in life ...
Brandon McCafferty +2 more
doaj +1 more source

