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High-Risk Human Papillomavirus Infection in Lung Cancer: Mechanisms and Perspectives
Lung cancer is a very prevalent and heterogeneous group of malignancies, and most of them are etiologically associated with tobacco smoking. However, viral infections have been detected in lung carcinomas, with high-risk human papillomaviruses (HR-HPVs ...
Julio C. Osorio +4 more
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Laryngeal infection with low-risk human papillomaviruses can cause recurrent respiratory papillomatosis (RRP), a disease with severe effects on vocal fold epithelium resulting in impaired voice function and communication. RRP research has been stymied by
Renee E. King +4 more
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Numerous large dark plaques developed over the ventrum, legs and head of a 9-year-old pug dog over a 4-year-period. Histology confirmed a diagnosis of viral pigmented plaque and a short section of a novel papillomavirus (PV) type was amplified using ...
John S. Munday +4 more
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High-risk human papillomaviruses (PV) account for approximately 600,000 new cancers per year. The early protein E8^E2 is a conserved repressor of PV replication, whereas E4 is a late protein that arrests cells in G2 and collapses keratin filaments to ...
Franziska Kuehner +6 more
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Tumeur de Buschke-Lowenstein à localisation pénienne
La tumeur de Buschke-Lowenstein (TBL) ou condylome acuminé géant (CAG) est une affection rare, d´origine virale appartenant au groupe des carcinomes verruqueux.
Ahmed Ibrahimi, Idriss Ziani
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Bovine Papillomavirus 1 Gets Out of the Flock: Detection in an Ovine Wart in Sicily
A proliferative cauliflower lesion was excised from the udder of a sheep. Histological investigation confirmed the macroscopic classification of the lesion as a papilloma, without any fibroblastic proliferation.
Federica Savini +10 more
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Papillomaviruses (PV) are associated with epithelial malignancies in animals, including cancer in humans. Limited knowledge exists regarding the evolutionary history of non-human PV.
Alba Frias-De-Diego +2 more
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Modeling HPV-Associated Disease and Cancer Using the Cottontail Rabbit Papillomavirus
Approximately 5% of all human cancers are attributable to human papillomavirus (HPV) infections. HPV-associated diseases and cancers remain a substantial public health and economic burden worldwide despite the availability of prophylactic HPV vaccines ...
Nancy M. Cladel +6 more
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Mastomys Species as Model Systems for Infectious Diseases
Replacements of animal models by advanced in vitro systems in biomedical research, despite exceptions, are currently still not satisfactory in reproducing the whole complexity of pathophysiological mechanisms that finally lead to disease.
Daniel Hasche, Frank Rösl
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Molecular Mechanisms of MmuPV1 E6 and E7 and Implications for Human Disease
Human papillomaviruses (HPVs) cause a substantial amount of human disease from benign disease such as warts to malignant cancers including cervical carcinoma, head and neck cancer, and non-melanoma skin cancer.
James C. Romero-Masters +2 more
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