Results 51 to 60 of about 322,248 (364)

Mastomys Species as Model Systems for Infectious Diseases

open access: yesViruses, 2019
Replacements of animal models by advanced in vitro systems in biomedical research, despite exceptions, are currently still not satisfactory in reproducing the whole complexity of pathophysiological mechanisms that finally lead to disease.
Daniel Hasche, Frank Rösl
doaj   +1 more source

Human papillomavirus-independent cervical cancer

open access: yesInternational Journal of Gynecological Cancer, 2021
Cervical cancer is the fourth most frequent cancer in women worldwide, representing nearly 8% of all female cancer deaths every year. The majority of cases of cervical cancer are caused by human papillomavirus (HPV); however, up to 5% of tumors are not ...
Andreina Fernandes   +4 more
semanticscholar   +1 more source

Prevalence and risk factors for oral human papillomavirus infection in Mexican HIV-infected men

open access: yesSalud Pública de México, 2018
Objective. To determine the prevalence and risk factors for oral high-risk human papillomavirus (HR-HPV) infection in human immunodeficiency virus (HIV)-infected men. Materials and methods.
Yuria Ablanedo-Terrazas   +6 more
doaj   +1 more source

The Mus musculus Papillomavirus Type 1 E7 Protein Binds to the Retinoblastoma Tumor Suppressor: Implications for Viral Pathogenesis

open access: yesmBio, 2021
The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous ...
Tao Wei   +6 more
doaj   +1 more source

Human Papillomavirus and Associated Cancers: A Review

open access: yesViruses
The human papillomavirus is the most common sexually transmitted infection in the world. Most HPV infections clear spontaneously within 2 years of infection; however, persistent infection can result in a wide array of diseases, ranging from genital warts
J. E. Jensen   +3 more
semanticscholar   +1 more source

Epidemiology of Any and Vaccine-Type Anogenital Human Papillomavirus Among 13-26-Year-Old Young Men After HPV Vaccine Introduction [PDF]

open access: yes, 2018
PURPOSE: The aims of this study were to determine prevalence of and factors associated with any human papillomavirus (HPV) and vaccine-type HPV among young men after vaccine introduction, stratified by vaccination status.
Bernstein, David I.   +7 more
core   +1 more source

A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels and activates the DNA damage response

open access: yesmBio
An interaction between human papillomavirus 16 (HPV16) E2 and the cellular proteins TopBP1 and BRD4 is required for E2 plasmid segregation function. The E2-TopBP1 interaction promotes increased mitotic E2 protein levels in U2OS and N/Tert-1 cells, as ...
Apurva T. Prabhakar   +9 more
doaj   +1 more source

Human Papillomavirus and Cervical Cancer

open access: yesEmerging Infectious Diseases, 2004
Though cervical cancer is highly curable when detected early, it remains one of the leading causes of cancer death in women worldwide. Early detection is effective because the precursor lesions evolve slowly into invasive cancer, typically over a period ...
E. Unger, E. Barr
semanticscholar   +1 more source

Keratinocyte differentiation-dependent human papillomavirus gene regulation [PDF]

open access: yes, 2017
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the differentiation process of the infected keratinocyte.
Graham, Sheila V.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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