Results 61 to 70 of about 175,854 (316)

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin

Chemistry – A European Journal, EarlyView.
The first high‐resolution structure of an OGRE‐derived G‐quadruplex from the chicken β‐globin replication origin reveals an intramolecular three‐layer (3+1) hybrid fold with a cytosine bulge and an unprecedented 5'‐outer‐quartet anti guanine, creating a distinctive surface for molecular recognition.
Yingying You, Monica Ching Suen, Haitao Miao, Yanyan Geng, Rahman Ud Din, Mu Yuan, Qiang Xue, Xiaoting Li, Naining Xu, Zhihong Guo, Hon‐Ming Lam, Kwok‐Wai Lo, Changdong Liu, Guang Zhu   +13 more
wiley   +1 more source

Burden and trends of type-specific human papillomavirus infections and related diseases in the latin america and Caribbean region. [PDF]

, 2008
We present the burden of human papillomavirus (HPV)-related cancers (cancers of the cervix, anogenital region, oral cavity and pharynx) in terms of incidence and mortality, for the countries of the Latin America and Caribbean region. The region is a high-
Piñeros, Marion, Almonte, Maribel, Curado, Maria-Paula, Clifford, Gary, Parkin, D Maxwell, Bruni, Laia   +5 more
core   +1 more source

Extended High‐Risk HPV Genotyping With BD Onclarity Enhances Anal Cancer Screening Among High‐Risk Populations: A Cross‐Sectional Study

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Anal cancer rates are rising among women, immunocompromised individuals, and Men who have sex with Men (MSM), independent of HIV status. While high‐resolution anoscopy remains the diagnostic standard, limited access has increased interest in alternative screening.
Daisy Maharjan, Joshua Waters, Melissa Randolph, Benjamin Shuler, Julie Borum, Sheila Segura   +5 more
wiley   +1 more source

Human papillomavirus detection in genital lesions by in situ hybridization and ultrastructural observations

Memorias do Instituto Oswaldo Cruz, 1994
Detection of papillomavirus DNA in sity hybridization technique was perfomed in 29 symptomatic patients (6 males and 23 females) during the period of 1989-1991 at the Clinic for Sexually Transmitted Diseases, Universidade Federal Fluminense, State of rio
L. H. S. Oliveira, I. C. P. P. Frugulhetti, M. R. L. Passos, S. M. B. Cavalcanti, M. E. F. Fonseca   +4 more
doaj   +1 more source

HPV Vaccination Coverage Rate in a Rural Area: An Observational, Retrospective, and Cohort Study

Vaccines, 2022
In order to reduce the incidence and mortality rate of cervical cancer, the World Health Organization (WHO) declared the Global Strategy Goal for 2030, advocating for reaching a vaccination coverage rate of >90% against human papillomavirus for girls by ...
Lara Colomé-Ceballos, Josep Lluís Clua-Espuny, José Fernández-Sáez, Concepción Ceballos-García, Natàlia Andrés-Cubells, Maria Jesús Pla-Farnós   +5 more
doaj   +1 more source

Turnaround Time Trends in Cervical Cytology Screening in South Africa, 2005–2023

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Timely cervical cytology results are crucial for effective screening and early management of precancerous lesions. However, many low‐ and middle‐income countries face delays in turnaround time (TAT). This study assessed TAT for cytology screening results in South Africa from 2005 to 2023 and identified factors associated with TAT ...
Sizeka Mashele, Nditsheni Nethavhakone, Matshediso Mohlala, Peace Ayeni, Johannes Molomo, Judith Mwansa‐Kambafwile, Jaimie Shing, Julia Bohlius, Mazvita Muchengeti   +8 more
wiley   +1 more source

Natural History of HPV Infection across the Lifespan: Role of Viral Latency

Viruses, 2017
Large-scale epidemiologic studies have been invaluable for elaboration of the causal relationship between persistent detection of genital human papillomavirus (HPV) infection and the development of invasive cervical cancer. However, these studies provide
Patti E. Gravitt, Rachel L. Winer
doaj   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

An in depth study of human papillomavirus diversity in South African women infected with HIV [PDF]

, 2009
Includes abstract. Includes bibliographical references (leaves 109-129).Cervical cancer is the second most common cancer affecting women and in most developing countries it remains the leading cause of cancer deaths.
Salimo, Anna T
core