Results 91 to 100 of about 933,669 (299)

p16 Overexpression and Human Papillomavirus Positivity in More Than 1000 Penile Cancers

International Journal of Cancer, EarlyView.
ABSTRACT Penile cancer is a severe disease, and a large proportion is related to high‐risk (hr) human papillomavirus (HPV). P16 is used as an immunohistochemical marker of HPV in clinical diagnostics. Population‐based data on the prevalence of p16 in penile cancer is scarce.
Marianne Gardar Stærk, Birgitte Grønkær Toft, Christina Stilling, Johanna Elversang, Sanne Kjær‐Frifeldt, Sonja Höhle Hjulskov, Sanja Stifter‐Vretenar, Marie Aarslev Schou, Mikael Aagaard, Peter Meidahl Petersen, Jakob Kristian Jakobsen, Christian Munk, Susanne Krüger Kjær   +12 more
wiley   +1 more source

Yield of endocervical curettage in detecting cervical intraepithelial neoplasia grade 2 or higher during colposcopy: A prospective, cross‐sectional study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 105-111, April 2025.
Abstract Objective This study assessed the prevalence and factors associated with detecting cervical intraepithelial neoplasia grade 2 or higher (CIN2+) via endocervical curettage (ECC) during colposcopy. Methods Between December 2020 and September 2023, a prospective, cross‐sectional study involving women with abnormal cervical cancer screening ...
Nida Jareemit, Lalita Theerarojanapong, Natthawadee Laokulrath, Vuthinun Achariyapota, Khemanat Khemworapong, Sompop Kuljarasnont, Pornporm Ittiamornlert, Vitcha Poonyakanok, Perapong Inthasorn   +8 more
wiley   +1 more source

Clearance of high‐risk human papillomavirus in patients with cervical intraepithelial neoplasia 2–3 after the loop electrosurgical excision procedure with negative resection margins

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aims to evaluate the longitudinal clearance rates of high‐risk human papillomavirus (hr‐HPV) and the incidence of clinical recurrence (defined by abnormal cytology or histologically confirmed cervical intraepithelial neoplasia; CIN) at 6 and 18 months post‐loop electrosurgical excision procedure (LEEP), characterizing the ...
Praew Sittichivapak, Pattama Chaopotong
wiley   +1 more source

Efficacy of topical imiquimod in HIV-positive patients with recurrent anal condylomata acuminata

Journal of Coloproctology, 2012
INTRODUCTION: Imiquimod is a topical chemotherapic and immunostimulant agent with antitumoral and antiviral activities, used for anal condylomata acuminata treatment, mainly in recurrences.
Sidney Roberto Nadal, Carmen Ruth Manzione, Fernanda Bellotti Formiga, Sérgio Henrique Couto Horta, Victor Edmond Seid   +4 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Acquired epidermodysplasia verruciformis due to multiple and unusual HPV infection among vertically-infected, HIV-positive adolescents in Zimbabwe. [PDF]

, 2012
BACKGROUND: We have previously described the presentation of epidermodysplasia verruciformis (EV)-like eruptions in almost a quarter of hospitalized adolescents with vertically-acquired human immunodeficiency virus (HIV) infection in Harare, Zimbabwe, a ...
Salisbury, JR, Miller, RF, Quint, W, Ferrand, RA, Nathoo, K, Ndhlovu, CE, de Koning, M, Munyati, S, Bunker, CB, Katsidzira, L, Corbett, EL, Meys, R, Lowe, SM, Sterling, JC   +13 more
core   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Quality of Life for Women with Human Papillomavirus-induced Lesions [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective To reveal the changes in the quality of life reported by women with Human papillomavirus (HPV)-induced lesions. Methods This is a cross-sectional, descriptive-exploratory study of a qualitative approach performed from June to August 2016. Semi-
Natália Maria Vieira Pereira-Caldeira, Fernanda Garcia Bezerra Góes, Maria Cristina Mendes de Almeida-Cruz, Juliano de Souza Caliari, Fernanda Maria Vieira Pereira-Ávila, Elucir Gir   +5 more
doaj   +2 more sources

Preliminary Development and Assessment of a Multiplex Assay for Human Papillomavirus Antibody Detection Using Commercial L1 Proteins

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed and assessed a new multiplex assay for the simultaneous detection of antibodies against multiple Human Papillomavirus (HPV) types. Using recombinant L1 protein, the assay quantifies IgG and IgA responses in human plasma, enabling comprehensive immune profiling across multiple high‐risk cancer‐associated HPV genotypes. This approach
Arash Aslanabadi, Maryam Karimi, Laura Powell, Lisa Schumaker, Ashley Shutt, Mahsa Hojabri, Rahim Abbasi, Søren M. Bentzen, Kevin J. Cullen, Trevor A. Crowell, Rebecca G. Nowak, Mohammad M. Sajadi   +11 more
wiley   +1 more source

Effect of Exosomes from Patients with Grade One Cervical Intraepithelial Neoplasia on Cell Cultures: A Preliminary Study

Cancer Management and Research, 2022
Luz Eugenia Alcántara-Quintana,1 Martha Esmeralda González-Pérez,2 Alejandra Loyola-Leyva,1 Yolanda Terán-Figueroa2 1Coordination for Innovation and Application of Science and Technology, Autonomous University of San Luis Potosí, San Luis Potosí, SLP ...
Alcántara-Quintana LE, González-Pérez ME, Loyola-Leyva A, Terán-Figueroa Y   +3 more
doaj