PI3Kγ in Tumour Inflammation: Bridging Immune Response and Cancer Progression—A Mini‐Review
Myeloid cell PI3Kγ can be activated by G Protein‐Coupled Receptors or Receptor Tyrosine Kinases. Once activated, PI3Kγ promotes integrin activation as well as Akt and mTOR activation, thereby promoting transcription of immune‐suppressive and pro‐angiogenic factors, such as Arginase, IL‐10, TGFβ and VEGF‐A.
Anghesom Ghebremedhin, Judith A. Varner
wiley +1 more source
Corrigendum: Associations of multi-human papillomavirus infections with expression of p16 in a cohort of women who underwent colposcopy: a retrospective study of 5165 patients. [PDF]
Zhang Y+11 more
europepmc +1 more source
The Role of the p16 and p53 Tumor Suppressor Proteins and Viral HPV16 E6 and E7 Oncoproteins in the Assessment of Survival in Patients with Head and Neck Cancers Associated with Human Papillomavirus Infections. [PDF]
Lifsics A+5 more
europepmc +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder+4 more
wiley +1 more source
Association Between Herpes Simplex Virus Type 2 and High-Risk Human Papillomavirus Infections: A Population Study of the National Health and Nutrition Examination Survey, 2009-2016. [PDF]
Liu C, Guo Y, Wang L, Guo R, Lei D.
europepmc +1 more source
Verruca Vulgaris Occurring on a Tattoo: Case Report and Review of Tattoo-Associated Human Papillomavirus Infections. [PDF]
Cohen PR.
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Association of human papillomavirus infection with carcinoma of the cervix uteri and its precursor lesions: theoretical and practical implications [PDF]
Karin Milde‐Langosch+2 more
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Multiprofessional Family Care for Women With Gynaecological Cancer
ABSTRACT Aim The aim of this study was to determine how family care is implemented in the care of women with gynaecological cancer from the perspective of health professionals in Finland. Design Multiphase convergent mixed‐methods research. Methods This study is based on two datasets collected from one Finnish university hospital. The first dataset was
Tea Metsävainio+4 more
wiley +1 more source
Concurrent and Concordant Anal and Oral Human PapillomaVirus Infections Are Not Associated with Sexual Behavior in At-Risk Males. [PDF]
Rollo F+8 more
europepmc +1 more source