Results 251 to 260 of about 85,427 (313)

Insulin‐Like Growth Factor 1 Receptor Expression for Predicting PD‑1/PD‑L1 Inhibitor Response in Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 112-123, February 2026.
ABSTRACT Objectives Insulin‐like growth factor 1 receptor (IGF‐1R) is crucial for immunological control and the development of different types of cancer. It is still uncertain how the expression of IGF‐1R impacts hypopharyngeal squamous cell carcinoma (HPSCC) and whether it has any predictive value for prognosis.
Wen‐Jing Li   +10 more
wiley   +1 more source

Yeast‐Based Biotechnology for Civilian Security

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała   +2 more
wiley   +1 more source

HPV vaccination following cervical intraepithelial neoplasia grade 2 diagnosis and risk of progression

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 2, Page 377-385, February 2026.
HPV vaccination in women undergoing active surveillance for CIN2 does not offer a protective effect against progression to CIN3+. Women should be informed that vaccination is not a substitute for clinical follow‐up and should be encouraged to adhere to recommended surveillance and treatment protocols Abstract Introduction Human papillomavirus (HPV ...
Dina O. Eriksen   +8 more
wiley   +1 more source

Stromal Defense Against Cancer: An Unprecedented Mechanism Limiting Cancer Invasion Into the Bone

open access: yesCancer Science, Volume 117, Issue 2, Page 308-315, February 2026.
The roles of nonimmune systems in tumor regulation remain largely undefined. This article introduces a new concept, “stromal defense against cancer (SDAC),” which is based on recent findings that the periosteum actively responds to tumor proximity and physically impedes tumor invasion into bone.
Masayuki Tsukasaki, Hiroshi Takayanagi
wiley   +1 more source

CDKN2A deletion in p16‐negative/HPV‐positive head and neck squamous cell carcinoma: Highlighting the molecular basis behind the limitation of relying on p16 immunohistochemistry as a surrogate marker for HPV involvement

open access: yesHistopathology, Volume 88, Issue 3, Page 664-672, February 2026.
We present a case series of HPV‐positive non‐keratinizing squamous cell carcinoma of the head and neck with discordant negative p16 staining due to CDKN2A deletion. These findings highlight the genomic basis behind the diagnostic pitfall of reliance on p16 immunohistochemistry as a surrogate marker of HPV and raise practice‐changing considerations for ...
Trevor Teich   +8 more
wiley   +1 more source

Human papillomavirus infection

Disease-a-Month, 2016
Human papillomavirus (HPV) is a DNA virus that causes a variety of conditions including common warts, condyloma acuminata (anogenital warts), and multiple malignancies involving the squamous epithelium. HPV is a unique oncogenic infectious agent that causes cervical cancer, the second most common cancer in women worldwide.
Jack N, Hutter, Catherine F, Decker
openaire   +2 more sources

Human papillomavirus infection

Journal of the American Academy of Dermatology, 1989
Of porri, verucae, and eondylomata of the pudenda. There remains a fourth species of venereal disease to be added to those which we have already described, viz, warty excrescences of the genitals, which sometimes succeed impure coition, but for the most part follow other porky disorders that have been iU managed. Sometimes they wither of themselves and
openaire   +3 more sources

Human Papillomavirus Infections

Advances in Pediatrics, 1992
Though the existence of disease associated with HPV has been documented for centuries, it has been only within the past 2 decades that we have recognized the clinical diversity and significant morbidity and mortality associated with HPV infections.
openaire   +2 more sources

Human papillomavirus infection

Journal of the American Academy of Dermatology, 1990
The human papillomavirus, well known as the etiologic agent of warts, has recently received much attention in the medical literature for its association with various cancers. This article discusses the virology, epidemiology, pathogenesis, immunology, clinical manifestations, and therapy for human papillomavirus infection.
openaire   +2 more sources

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