Results 31 to 40 of about 306,192 (264)

Jab1, a Novel Protease-activated Receptor-2 (PAR-2)-interacting Protein, Is Involved in PAR-2-induced Activation of Activator Protein-1 [PDF]

Journal of Biological Chemistry, 2006
Protease-activated receptor-2 (PAR-2), a G protein-coupled receptor for trypsin and tryptase, exerts important physiological and pathological functions in multiple systems. However, unlike PAR-1, the PAR-2-mediated intracellular signal transductions are hardly known.
Weibo, Luo, Yingfei, Wang, Theodor, Hanck, Rolf, Stricker, Georg, Reiser   +4 more
openaire   +2 more sources

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The role of protease-activated receptor-2 on pulmonary neutrophils in the innate immune response to cockroach allergen

Journal of Inflammation, 2012
Background Serine proteases in German cockroach (GC) have been shown to mediate allergic airway inflammation through the activation of protease activated receptor (PAR)-2.
Lutfi Riad, Lewkowich Ian P, Zhou Ping, Ledford John R, Page Kristen   +4 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Proteinase-activated receptor-2: two potential inflammatory mediators of the gastrointestinal tract in Atlantic salmon

Journal of Inflammation, 2008
Proteinase-activated receptor 2 (PAR-2), activated by trypsin and other serine proteinases, is a key initiator of inflammatory responses in the intestine of mammals.
Valen Elin, Lilleeng Einar, Thorsen Jim, Krogdahl Åshild   +3 more
doaj   +1 more source

A long-term time series of global and diffuse photosynthetically active radiation in the Mediterranean: interannual variability and cloud effects [PDF]

Atmospheric Chemistry and Physics, 2018
Measurements of global and diffuse photosynthetically active radiation (PAR) have been carried out on the island of Lampedusa, in the central Mediterranean Sea, since 2002.
P. Trisolino, P. Trisolino, A. di Sarra, F. Anello, C. Bommarito, T. Di Iorio, D. Meloni, F. Monteleone, G. Pace, S. Piacentino, D. Sferlazzo   +10 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Plaies Pénétrantes Cervicales par Tentative d’Autolyse par Lame de Rasoir : à Propos de 2 Cas

Health Research in Africa
RÉSUMÉ Les plaies cervicales auto-infligées représentent des urgences chirurgicales et psychiatriques complexes. Nous rapportons deux cas pris en charge en 2023 mettant en lumière ce défi.
Mboua Ndenga VJ, Atangana EHN, Bisay SUB, Mossus Y, Eya MES, Ntone S, Ngo Nyeki AR, Messakop MY, Bilo’o MLL, Melleu V, N’djeudjui C, Sikati WS, Ekono M, Bengono BRS   +13 more
doaj   +1 more source

Relationship between photosynthetically active radiation and global radiation in Petrolina and Brasília, Brazil

Revista Brasileira de Engenharia Agrícola e Ambiental, 2021
Photosynthetically active radiation (PAR) comprises the spectral range of global solar radiation (Rs) that is highly related to vegetation productivity.
Lady L. M. Custódio, Bernardo B. da Silva, Carlos A. C. dos Santos   +2 more
doaj   +1 more source

Characterization of apical and basolateral PAR‐2

The FASEB Journal, 2010
Studies suggest there are two distinct pools of protease‐activated receptor‐2 (PAR‐2) present in colonic epithelial cells: an apical pool exposed to the lumen, and a basolateral pool exposed to bloodstream.
openaire   +1 more source