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Comparative Evaluation of Release Profiles from Hydrogel, Oleogel, and Bigel Systems Containing Model Radiopharmaceuticals for Buccal Delivery. [PDF]
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Dermatitis, 2019
Parabens now being formally declared as the American Contact Dermatitis Society (non)allergen of the year, the allergologic concerns regarding parabens raised during the past century are no longer a significant issue. The more recent toxicological concerns regarding parabens are more imposing, stemming from the gravity of the noncutaneous adverse ...
Anthony F, Fransway +3 more
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Parabens now being formally declared as the American Contact Dermatitis Society (non)allergen of the year, the allergologic concerns regarding parabens raised during the past century are no longer a significant issue. The more recent toxicological concerns regarding parabens are more imposing, stemming from the gravity of the noncutaneous adverse ...
Anthony F, Fransway +3 more
openaire +2 more sources
JAMA: The Journal of the American Medical Association, 1977
A hydrocortisone preparation containing methylparaben and propylparaben provoked bronchospasm and pruritus when given intravenously to an asthmatic patient, whereas another hydrocortisone preparation without paraben preservative did not. Direct and passive transfer (Prausnitz-Küstner) skin tests for immediate hypersensitivity to parabens were positive.
J E, Nagel, J T, Fuscaldo, P, Fireman
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A hydrocortisone preparation containing methylparaben and propylparaben provoked bronchospasm and pruritus when given intravenously to an asthmatic patient, whereas another hydrocortisone preparation without paraben preservative did not. Direct and passive transfer (Prausnitz-Küstner) skin tests for immediate hypersensitivity to parabens were positive.
J E, Nagel, J T, Fuscaldo, P, Fireman
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International Journal of Dermatology, 1995
Abstract Background. To test the reliability and reproducibility of the patch test with a paraben mix, we added a second paraben mix allergen to our standard tray and compared the results achieved with these two allergens. Methods. Two hundred and fifteen consecutive patients, undergoing patch testing with a standard series, were simultaneously tested ...
R, Wolf, S, Brenner
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Abstract Background. To test the reliability and reproducibility of the patch test with a paraben mix, we added a second paraben mix allergen to our standard tray and compared the results achieved with these two allergens. Methods. Two hundred and fifteen consecutive patients, undergoing patch testing with a standard series, were simultaneously tested ...
R, Wolf, S, Brenner
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Journal of pharmaceutical and biomedical analysis, 1997
A high performance liquid chromatographic technique has been used to determine phenoxetol, methyl paraben, ethyl paraben, n-propyl paraben, iso-butyl paraben, n-butyl paraben and croconazole.HCl. The method developed involves isocratic, reversed phase chromatography. The range of quantitation was found to be 90-135.0 micrograms ml-1 for phenoxetol, 2.0-
M J, Akhtar +3 more
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A high performance liquid chromatographic technique has been used to determine phenoxetol, methyl paraben, ethyl paraben, n-propyl paraben, iso-butyl paraben, n-butyl paraben and croconazole.HCl. The method developed involves isocratic, reversed phase chromatography. The range of quantitation was found to be 90-135.0 micrograms ml-1 for phenoxetol, 2.0-
M J, Akhtar +3 more
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JAMA: The Journal of the American Medical Association, 1967
Four cases of allergic contact sensitivity to alkyl esters ofp-hydroxybenzoic acid (parabens) were detected during routine closed patch tests on 91 patients with contact dermatitis. All four patients had refractory dermatitis of unknown cause and all were using topical medications containing parabens as preservative.
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Four cases of allergic contact sensitivity to alkyl esters ofp-hydroxybenzoic acid (parabens) were detected during routine closed patch tests on 91 patients with contact dermatitis. All four patients had refractory dermatitis of unknown cause and all were using topical medications containing parabens as preservative.
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Topical Parabens: Benefits and Risks
Dermatology, 1977Parabens are the most frequently used preservative in dermatological medications. Some allergies have been reported to parabens, but these risks must be considered with respect to the benefits of parabens in concentrations used as preservatives in dermatological formulations.
O J, Lorenzetti, T C, Wernet
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JAMA, 1968
Paraben esters are incorporated in most dermatologic and cosmetic creams and lotions as preservatives. A two-year clinical study on the allergenic potential of these bacteriostatic and fungistatic chemicals showed that of 273 consecutive patients with chronic dermatitis who were routinely patch tested to 5% paraben in petrolatum had paraben allergy, an
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Paraben esters are incorporated in most dermatologic and cosmetic creams and lotions as preservatives. A two-year clinical study on the allergenic potential of these bacteriostatic and fungistatic chemicals showed that of 273 consecutive patients with chronic dermatitis who were routinely patch tested to 5% paraben in petrolatum had paraben allergy, an
openaire +2 more sources