Results 121 to 130 of about 4,522 (174)
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JAMA, 1977
A hydrocortisone preparation containing methylparaben and propylparaben provoked bronchospasm and pruritus when given intravenously to an asthmatic patient, whereas another hydrocortisone preparation without paraben preservative did not. Direct and passive transfer (Prausnitz-Küstner) skin tests for immediate hypersensitivity to parabens were positive.
J E, Nagel, J T, Fuscaldo, P, Fireman
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A hydrocortisone preparation containing methylparaben and propylparaben provoked bronchospasm and pruritus when given intravenously to an asthmatic patient, whereas another hydrocortisone preparation without paraben preservative did not. Direct and passive transfer (Prausnitz-Küstner) skin tests for immediate hypersensitivity to parabens were positive.
J E, Nagel, J T, Fuscaldo, P, Fireman
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JAMA: The Journal of the American Medical Association, 1967
Four cases of allergic contact sensitivity to alkyl esters ofp-hydroxybenzoic acid (parabens) were detected during routine closed patch tests on 91 patients with contact dermatitis. All four patients had refractory dermatitis of unknown cause and all were using topical medications containing parabens as preservative.
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Four cases of allergic contact sensitivity to alkyl esters ofp-hydroxybenzoic acid (parabens) were detected during routine closed patch tests on 91 patients with contact dermatitis. All four patients had refractory dermatitis of unknown cause and all were using topical medications containing parabens as preservative.
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Solubility of Parabens in Alcohols
Journal of Pharmaceutical Sciences, 1969The solubilities of methyl, ethyl, propyl, and butyl parabens have been determined in a series of normal alcohols. This pure solvent scan indicated a dielectric requirement of about 14 for the subject compounds. Another dielectric requirement may be postulated to exist at a value of about 30.
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Thermodynamics of Aqueous Solutions of Parabens
Journal of Pharmaceutical Sciences, 1978The solubility of a related series of parabens was determined in water at four temperatures. The parabens chosen were the methyl through n-butyl p-hydroxybenzoates, and the temperature variations were 5 degrees increments from 25 to 40 degrees. These solutes are useful preservatives, especially combinations of the methyl and propyl ester derivatives ...
K S, Alexander +3 more
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Sorption of Parabens by Flexible Tubings
Pharmaceutical Development and Technology, 2001Flexible tubings are extensively used in pharmaceuticals, food industry, and in hospitals. This study was undertaken to compare various flexible tubings to determine their sorption characteristics, using methyl and propyl parabens. After 24 h, some tubings showed 100% sorption of propylparaben and over 40% for methylparaben.
S M, Bahal, J M, Romansky
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Solubility of Parabens in Syrup Vehicles
Journal of Pharmaceutical Sciences, 1966The solubilities of methyl, ethyl, propyl, butyl, and benzylparabens have been determined in sucrose vehicles of varying concentration. These syrup vehicles possess dielectric constants less than pure water, their respective dielectric constants decreasing with increasing sucrose concentration.
A N, Paruta, B B, Sheth
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JAMA, 1968
Paraben esters are incorporated in most dermatologic and cosmetic creams and lotions as preservatives. A two-year clinical study on the allergenic potential of these bacteriostatic and fungistatic chemicals showed that of 273 consecutive patients with chronic dermatitis who were routinely patch tested to 5% paraben in petrolatum had paraben allergy, an
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Paraben esters are incorporated in most dermatologic and cosmetic creams and lotions as preservatives. A two-year clinical study on the allergenic potential of these bacteriostatic and fungistatic chemicals showed that of 273 consecutive patients with chronic dermatitis who were routinely patch tested to 5% paraben in petrolatum had paraben allergy, an
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Parabens and their effects on the endocrine system
Molecular and Cellular Endocrinology, 2018Preservatives (ingredients which inhibit growth of microorganisms) are used to prolong shelf life of various foods, cosmetics, and pharmaceutical products. Parabens are one of the most popular preservatives used in the aforementioned products and is currently being used worldwide. Parabens are easily absorbed by the human body. Thus, it is important to
Karolina Nowak +3 more
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Topical Parabens: Benefits and Risks
Dermatologica, 2009Parabens are the most frequently used preservative in dermatological medications. Some allergies have been reported to parabens, but these risks must be considered with respect to the benefits of parabens in concentrations used as preservatives in dermatological formulations.
O J, Lorenzetti, T C, Wernet
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