Results 71 to 80 of about 2,657 (184)

Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness

Experimental Physiology, EarlyView.
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier, Danielle K. Greaves, J. Kevin Shoemaker, Philippe Arbeille, Richard L. Hughson, Andrew D. Robertson   +5 more
wiley   +1 more source

Milton's Macbeth: Time, Irony, and Evil in Paradise Lost

Milton Quarterly, EarlyView.
Gary Kuchar
wiley   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Pharmacological Stimulation of Type 5 Adenylyl Cyclase Stabilizes Heart Rate Under Both Microgravity and Hypergravity Induced by Parabolic Flight

Journal of Pharmacological Sciences, 2012
We previously demonstrated that type 5 adenylyl cyclase (AC5) functions in autonomic regulation in the heart. Based on that work, we hypothesized that pharmacological modulation of AC5 activity could regulate the autonomic control of the heart rate under
Yunzhe Bai, Takashi Tsunematsu, Qibin Jiao, Yoshiki Ohnuki, Yasumasa Mototani, Kouichi Shiozawa, Meihua Jin, Wenqian Cai, Hui-Ling Jin, Takayuki Fujita, Yasuhiro Ichikawa, Kenji Suita, Reiko Kurotani, Utako Yokoyama, Motohiko Sato, Kousaku Iwatsubo, Yoshihiro Ishikawa, Satoshi Okumura   +17 more
doaj   +1 more source

Blood flow restriction exercise during microgravity exposure in parabolic flight

Experimental Physiology, EarlyView.
Abstract This case report evaluates whether it is possible to perform blood flow restriction (BFR) exercise during exposure to microgravity. The objectives were three‐fold: (1) to determine if a personalised tourniquet system (PTS) hardware technology performs nominally and enables BFR exercise in microgravity; (2) to determine if BFR augments the ...
Yannick Laflamme, Etienne Chassé, Luke Hughes   +2 more
wiley   +1 more source

Seizing opportunities and navigating the challenges of spaceflight research as an early career researcher

Experimental Physiology, EarlyView.
Colleen S. Deane
wiley   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

TEMPUS—A microgravity electromagnetic levitation facility for parabolic flights

Review of Scientific Instruments
During the ∼22 s lasting free fall phase in an aircraft flying a parabola, the aboard installed electromagnetic levitation facility “TEMPUS” is used to investigate contactless and undisturbed of gravity induced convection thermophysical properties and microstructure formations of hot and highly reactive metal or semiconductor melts.
G. Lohöfer, M. Beckers, T. Blumberg, D. Bräuer, S. Schneider, T. Volkmann, A. Meyer   +6 more
openaire   +3 more sources

Hyper‐buoyancy flotation increases cervical disc height and reduces vertebral stiffness, with only partial reversal after acute 1 g axial loading

Experimental Physiology, EarlyView.
Abstract Exposure to microgravity is associated with stature increases, moderate‐to‐severe back/neck pain and elevated lumbar and cervical intervertebral disc (IVD) herniation risk post‐flight. Whilst lumbar pathophysiology has been investigated, little attention has been placed on the cervical spine.
D. Marcos‐Lorenzo, P. Hernández Bernal, R. Fernández Corujo, A. Gil Martínez, J. Swanenburg, D. A. Green   +5 more
wiley   +1 more source

Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity

Frontiers in Physiology
IntroductionThe effect of micro-gravity on the lumbar and in particular thoracic regions is poorly understood. The aim of this study was to evaluate spinal curvature across the lumbar and thoracic region, and extensor muscle activity during acute micro ...
Anita Meinke, Alessandro Longhi Baez, Niklas Wiesmann, Oliver Ullrich, David A. Green, David A. Green, Marcel Egli, Marcel Egli, Jaap Swanenburg, Jaap Swanenburg   +9 more
doaj   +1 more source