Results 161 to 170 of about 10,332 (185)
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Paracetamol (acetaminophen) poisoning
Pharmacology & Therapeutics, 1993Paracetamol poisoning caused by intentional overdose remains a common cause of morbidity. In this article the mechanism of toxicity and the clinical effects and treatment of poisoning, including specific antidotal therapy, are reviewed. Areas for further research directed at reducing morbidity and mortality from paracetamol poisoning are considered.
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Companion Animal, 2016
Paracetamol is a very common and readily available analgesic, alone or in combination with other drugs in some cold and flu products. In dogs, paracetamol at low doses is metabolised to non-toxic metabolites, but these pathways become saturated in overdose, leading to metabolism by other pathways resulting in the production of toxic metabolites.
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Paracetamol is a very common and readily available analgesic, alone or in combination with other drugs in some cold and flu products. In dogs, paracetamol at low doses is metabolised to non-toxic metabolites, but these pathways become saturated in overdose, leading to metabolism by other pathways resulting in the production of toxic metabolites.
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Treatments for paracetamol poisoning
BMJ, 2016A 24 year old woman is brought to the emergency department semi-conscious after a suspected overdose; empty packs of paracetamol (acetaminophen) and diazepam are found with her. She is also taking carbamazepine for seizures. Her paracetamol concentration at the time of admission is 100 mg/L (660 µmol/L); she probably ingested the pills four to eight ...
Nicholas A, Buckley +2 more
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Paracetamol poisoning in children
The Indian Journal of Pediatrics, 1998Paracetamol (acetaminophen) has become an antipyretic drug of choice. Due to its widespread use, toxicity secondary to overdose has increased in recent years. Children are especially vulnerable to accidental exposure due to non availability of child proof containers in India.
S B, Lall, R, Paul
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Management of paracetamol poisoning
Trends in Pharmacological Sciences, 2003Paracetamol is the most common substance involved in self-poisoning in the UK. The main advances made over the past five years in the management of early paracetamol poisoning, identification of risk factors for paracetamol poisoning, understanding of the mechanisms and management of late paracetamol poisoning and issues concerning the prevention of ...
Dargan, Paul I, Jones, Alison L
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Management of paracetamol poisoning
BMJ, 2011#### Summary points Paracetamol (acetaminophen) is an effective oral analgesic, with few adverse effects when used at the recommended dose. Nevertheless, paracetamol poisoning is common and potentially fatal.1 It is a leading cause of acute liver failure in the United Kingdom2 and the United States.3 Potential liver damage, predicted from blood ...
Robin E, Ferner +2 more
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Accidental paracetamol poisoning
Medical Journal of Australia, 2007John S, Lubel +2 more
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Paracetamol (acetaminophen) poisoning
The Lancet, 1995J A, Vale, A T, Proudfoot
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