IL-6 Degradation by Secreted Proteases From <i>Paracoccidioides restrepiensis</i>. [PDF]
Int J MicrobiolParacoccidioidomycosis is a systemic fungal disease caused by Paracoccidioides spp., predominantly affecting populations in Latin America, with Brazil reporting the highest number of cases. The infection is associated with severe pulmonary and systemic manifestations. Previous studies have highlighted the role of fungal proteases in adhesion, invasion,
de Oliveira P +9 more
europepmc +2 more sources
Evaluation of commercial immunodiffusion reagents for detecting serum anti-Paracoccidioides antibodies [PDF]
Revista da Sociedade Brasileira de Medicina TropicalBackground: Accurate diagnosis of paracoccidioidomycosis is crucial for improving patient outcomes. Paracoccidioides antibody detection by double immunodiffusion (DID) is a convenient diagnostic tool, but testing performance can vary based on certain ...
Regielly Caroline Raimundo Cognialli +2 more
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Paracoccidioides spp.: the structural characterization of extracellular matrix, expression of glucan synthesis and associated genes and adhesins during biofilm formation [PDF]
Frontiers in MicrobiologyThe genus Paracoccidioides includes Paracoccidioides lutzii and the Paracoccidioides brasiliensis complex, which comprises four phylogenetic species. A key feature distinguishing planktonic growth from biofilm is the presence of a 3D extracellular matrix
Lariane Teodoro Oliveira +7 more
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Fungal-host interactions: insights into microRNA in response to Paracoccidioides species [PDF]
Memorias do Instituto Oswaldo Cruz, 2020 BACKGROUND Paracoccidioides spp. causes paracoccidioidomycosis (PCM), an important and frequent systemic mycosis that occurs in Latin America. The infectious process begins with contact between the fungus and lung cells, and the molecular pattern of this
Junya de Lacorte Singulani +6 more
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Genus paracoccidioides: Species recognition and biogeographic aspects. [PDF]
PLoS ONE, 2012 BACKGROUND: Paracoccidioidomycosis is a systemic mycosis caused by Paracoccidioides brasiliensis (species S1, PS2, PS3), and Paracoccidioides lutzii. This work aimed to differentiate species within the genus Paracoccidioides, without applying multilocus ...
Raquel Cordeiro Theodoro +6 more
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Evaluation of Caenorhabditis elegans as a host model for Paracoccidioides brasiliensis and Paracoccidioides lutzii [PDF]
Pathogens and Disease, 2018 Paracoccidioidomycosis is a systemic fungal infection affecting mainly Latin American countries that is caused by Paracoccidioides brasiliensis and Paracoccidioides lutzii. During the study of fungal pathogenesis, in vivo studies are crucial to understand the overall mechanisms involving the infection as well as to search for new therapeutic treatments
Scorzoni, Liliana +6 more
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The Trojan Horse Model in Paracoccidioides: A Fantastic Pathway to Survive Infecting Human Cells
Frontiers in Cellular and Infection Microbiology, 2021 Paracoccidioidomycosis (PCM) is the most relevant systemic endemic mycosis limited to Latin American countries. The etiological agents are thermally dimorphic species of the genus Paracoccidioides.
Gustavo Giusiano
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Molecular detection of Paracoccidioides in soil from an urban area of southern Brazil
Revista da Sociedade Brasileira de Medicina Tropical, 2020 INTRODUCTION: Previous studies that detected Paracoccidioides spp. DNA in soil taken from rural areas have shown this to be a valuable tool for ecological and epidemiological studies. This study reports the detection of Paracoccidioides spp. DNA in soil
Josiara Furtado Mendes +4 more
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Paracoccidioides brasiliensis habitat: far beyond armadillo burrows? [PDF]
Memorias do Instituto Oswaldo Cruz, 2020 Paracoccidioides spp. isolation from environmental samples is rare and hardly reproducible. Molecular techniques have facilitated the fungal detection. However, it can be still difficult. Some strategies to enhance the capacity of DNA detection have been
Priscila Marques de Macedo +7 more
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mBio, 2020 The fungus Paracoccidioides is a prevalent human pathogen endemic to South America. The genus is composed of five species. In this report, we use 37 whole-genome sequences to study the allocation of genetic variation in Paracoccidioides.
Heidi Mavengere +7 more
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