Results 31 to 40 of about 4,451 (178)

Genome Diversity, Recombination, and Virulence across the Major Lineages of Paracoccidioides

mSphere, 2016
The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic to Latin America.
José F. Muñoz, Rhys A. Farrer, Christopher A. Desjardins, Juan E. Gallo, Sean Sykes, Sharadha Sakthikumar, Elizabeth Misas, Emily A. Whiston, Eduardo Bagagli, Celia M. A. Soares, Marcus de M. Teixeira, John W. Taylor, Oliver K. Clay, Juan G. McEwen, Christina A. Cuomo   +14 more
doaj   +1 more source

Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses

IMA Fungus, 2020
Fungi of the complex Paracoccidioides spp. are thermodimorphic organisms that cause Paracoccidioidomycosis, one of the most prevalent mycoses in Latin America.
Luiz Paulo Araújo Santos, Leandro do Prado Assunção, Patrícia de Souza Lima, Gabriel Brum Tristão, Matthias Brock, Clayton Luiz Borges, Mirelle Garcia Silva-Bailão, Célia Maria de Almeida Soares, Alexandre Melo Bailão   +8 more
doaj   +1 more source

Epidemiology of paracoccidioidomycosis in Venezuela: a retrospective study from 1954 to 2019

Memorias do Instituto Oswaldo Cruz, 2021
BACKGROUND Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America. Etiological agents are Paracoccidioides species that diverge phylogenetically throughout South America. OBJECTIVES This study aimed to document the epidemiology of
Primavera Alvarado, Marcus de Melo Teixeira, Elsy Cavallera, Hugo Costa Paes, Giovanni Guerra, Gerardo Santander, Rommie Merino-Alado   +6 more
doaj   +1 more source

Comparative proteomics in the genus Paracoccidioides

Fungal Genetics and Biology, 2013
The genus Paracoccidioides comprises a complex of phylogenetic species of dimorphic pathogenic fungi, the etiologic agents of paracoccidioidomycosis (PCM), a disease confined to Latin America and of marked relevance in its endemic areas due to its high frequency and severity.
Pigosso, Laurine Lacerda, Parente, Ana Flávia Alves, Coelho, Alexandre Siqueira Guedes, Silva, Luciano Paulino, Borges, Clayton Luiz, Bailão, Alexandre Melo, Soares, Célia Maria de Almeida   +6 more
openaire   +2 more sources

Melanin as a Virulence Factor in Different Species of Genus Paracoccidioides

Journal of Fungi, 2020
Paracoccidioidomycosis (PCM) is a granulomatous systemic mycosis caused by the thermo-dimorphic fungi of the genus Paracoccidioides. Melanin production by fungi can affect their pathogenesis and virulence.
Elúzia C. P. Emidio, Martha E. Urán J., Leandro B. R. Silva, Lucas S. Dias, Mariana Doprado, Joshua D. Nosanchuk, Carlos Pelleschi Taborda   +6 more
doaj   +1 more source

Paracoccidioidomycosis Protective Immunity

Journal of Fungi, 2021
Protective immunity against Paracoccidioides consists of a stepwise activation of numerous effector mechanisms that comprise many cellular and soluble components.
Eva Burger
doaj   +1 more source

Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus.

PLoS Neglected Tropical Diseases, 2015
BackgroundHypoxic microenvironments are generated during fungal infection. It has been described that to survive in the human host, fungi must also tolerate and overcome in vivo microenvironmental stress conditions including low oxygen tension; however ...
Patrícia de Sousa Lima, Dawoon Chung, Alexandre Melo Bailão, Robert A Cramer, Célia Maria de Almeida Soares   +4 more
doaj   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

Fatal Fungemia due to Paracoccidioides lutzii [PDF]

The American Society of Tropical Medicine and Hygiene, 2014
We report the first case of fungemia caused by Paracoccidioides lutzii in a 51-year-old male farm worker from the central-west region of Brazil. The fungus was isolated from blood cultures and the species was confirmed by phylogenetic identification. Despite specific treatment and intensive care, the patient died 39 days after admission.
Rosane Christine, Hahn, Anderson Messias, Rodrigues, Cor Jesus Fernandes, Fontes, Andreia Ferreira, Nery, Tomoko, Tadano, Luiz de Pádua, Queiroz, Zoilo Pires, de Camargo   +6 more
openaire   +2 more sources

Emerging Antifungal Resistance in Tropical Mycoses: A Genomic and Clinical Perspective From Endemic Zones

Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.
Antifungal resistance in tropical mycoses is an increasingly important component of the global antimicrobial resistance crisis, particularly in endemic regions where diagnostic capacity, therapeutic options, and surveillance systems are limited. This review synthesizes clinical, environmental, and genomic evidence on resistance in major endemic and ...
Meral Miraloglu
wiley   +1 more source