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Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis.
Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, is coupled with a thermally ...
Christopher A Desjardins +41 more
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Genome Diversity, Recombination, and Virulence across the Major Lineages of
The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic to Latin America.
José F. Muñoz +14 more
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Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses
Fungi of the complex Paracoccidioides spp. are thermodimorphic organisms that cause Paracoccidioidomycosis, one of the most prevalent mycoses in Latin America.
Luiz Paulo Araújo Santos +8 more
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Epidemiology of paracoccidioidomycosis in Venezuela: a retrospective study from 1954 to 2019
BACKGROUND Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America. Etiological agents are Paracoccidioides species that diverge phylogenetically throughout South America. OBJECTIVES This study aimed to document the epidemiology of
Primavera Alvarado +6 more
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Comparative proteomics in the genus Paracoccidioides
The genus Paracoccidioides comprises a complex of phylogenetic species of dimorphic pathogenic fungi, the etiologic agents of paracoccidioidomycosis (PCM), a disease confined to Latin America and of marked relevance in its endemic areas due to its high frequency and severity.
Pigosso, Laurine Lacerda +6 more
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Melanin as a Virulence Factor in Different Species of Genus Paracoccidioides
Paracoccidioidomycosis (PCM) is a granulomatous systemic mycosis caused by the thermo-dimorphic fungi of the genus Paracoccidioides. Melanin production by fungi can affect their pathogenesis and virulence.
Elúzia C. P. Emidio +6 more
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Paracoccidioidomycosis Protective Immunity
Protective immunity against Paracoccidioides consists of a stepwise activation of numerous effector mechanisms that comprise many cellular and soluble components.
Eva Burger
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Fatal Fungemia due to Paracoccidioides lutzii [PDF]
We report the first case of fungemia caused by Paracoccidioides lutzii in a 51-year-old male farm worker from the central-west region of Brazil. The fungus was isolated from blood cultures and the species was confirmed by phylogenetic identification. Despite specific treatment and intensive care, the patient died 39 days after admission.
Rosane Christine, Hahn +6 more
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ABSTRACT Objective To analyse mortality, hospitalisations and in‐hospital mortality related to paracoccidioidomycosis (PCM) in Brazil, 2000–2024, from a spatio‐temporal and social inequalities perspective. Methods We conducted a mixed ecological study using death certificates from the Mortality Information System and hospital admissions from the ...
Anderson Fuentes Ferreira +9 more
wiley +1 more source
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo +9 more
wiley +1 more source

