Results 51 to 60 of about 11,391 (207)
Detection of the basement membrane-degrading proteolytic activity of Paracoccidioides brasiliensis after SDS-PAGE using agarose overlays containing Abz-MKALTLQ-EDDnp [PDF]
We have characterized, in the Paracoccidioides brasiliensis yeast phase, an exocellular SH-dependent serine proteinase activity against Abz-MKRLTL-EDDnp and analogous fluorescent-quenched peptides, and showed that it is also active against constituents ...
Carmona, Adriana Karaoglanovic +4 more
core +4 more sources
Random sequencing ofParacoccidioides brasiliensisgenes [PDF]
Paracoccidioides brasiliensis genome has been reported as having a size of about 30 Mb. By digestion of genomic DNA from strain IVICPb 73 (ATCC 32071), we have constructed a DNA library with an insert size average of 8 kb in Escherichia coli XL1 Blue.
Cristina, Reinoso +3 more
openaire +3 more sources
BackgroundHypoxic microenvironments are generated during fungal infection. It has been described that to survive in the human host, fungi must also tolerate and overcome in vivo microenvironmental stress conditions including low oxygen tension; however ...
Patrícia de Sousa Lima +4 more
doaj +1 more source
Serology of paracoccidioidomycosis [PDF]
This review provides the background for understanding the role of a battery of diagnostic methods in paracoccidioidomycosis (PCM). This systemic mycosis is a disease endemic in many regions of Latin America, with sporadic cases also occurring throughout ...
Camargo, Zoilo Pires de
core +1 more source
ABSTRACT Objective To analyse mortality, hospitalisations and in‐hospital mortality related to paracoccidioidomycosis (PCM) in Brazil, 2000–2024, from a spatio‐temporal and social inequalities perspective. Methods We conducted a mixed ecological study using death certificates from the Mortality Information System and hospital admissions from the ...
Anderson Fuentes Ferreira +9 more
wiley +1 more source
ABSTRACT Extracellular vesicles (EVs) released by Aspergillus fumigatus play key roles in fungal–host communication. Similar to synthetic nanoparticles, fungal EVs acquire a biomolecular corona composed of a tightly bound “hard” corona layer of fungal proteins and a dynamic “soft” layer of host‐derived molecules adsorbed upon contact with biological ...
Lucas Fabrício Bahia Nogueira +10 more
wiley +1 more source
Paracoccidioides brasiliensis GP43-derived peptides are potent modulators of local and systemic inflammatory response [PDF]
Paracoccidioidomycosis is a systemic granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis. Its major antigen is a 43 kDa glycoprotein whose peptides embody different functions: P10 peptide, a T-cell epitope, :induces ...
Feitosa, Luciano dos Santos +7 more
core +2 more sources
The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen +3 more
wiley +1 more source
Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Brazil. The disease is caused by dimorphic fungi nested within the Paracoccidioides genus.
Alessandra G. Krakhecke-Teixeira +10 more
doaj +1 more source
Diversity in Paracoccidioides brasiliensis. the PbGP43 gene as a genetic marker [PDF]
Paracoccidioides brasiliensis is a temperature-dependent dimorphic fungus and the agent of paracoccidioidomycosis (PCM), which is prevalent in rural workers of Latin American countries. Until a decade ago, most of the studies involving P.
Cisalpino, Patricia Silva +2 more
core +1 more source

