Clinical Patterns of Osteoarticular, Bone Marrow and Urogenital Paracoccidioidomycosis
ABSTRACT Background Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America, classically characterized by pulmonary, mucosal and lymphatic involvement. Extrapulmonary manifestations affecting uncommon organs remain poorly characterized and may contribute to diagnostic delay and adverse outcomes. Methods We conducted a retrospective
Wdson Luis Lima Kruschewsky +7 more
wiley +1 more source
DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis induces long-term protection in presence of regulatory T cells [PDF]
Paracoccidioidomycosis is a granulomatous systemic mycosis endemic in Brazil and other Latin America countries. A DNA vaccine encoding the inununoprotective peptide 10 (P10) significantly reduced the fungal burden in mice when given prior to or after ...
Amorim, Juliana de +6 more
core +2 more sources
Helminths as architects of trained tolerance: implications for human health
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz +2 more
wiley +1 more source
Extracellular Vesicle-Associated Transitory Cell Wall Components and Their Impact on the Interaction of Fungi with Host Cells [PDF]
Submitted by Fabricia Pimenta (fabricia.pimenta@cdts.fiocruz.br) on 2018-06-29T18:34:23Z No. of bitstreams: 1 ve_Marcio_Rodrigues_etal_CDTS_2016.pdf: 690221 bytes, checksum: a96164d483123b78f71bffabda9ffa1b (MD5)Approved for entry into archive by ...
Joshua D. Nosanchuk +6 more
core +1 more source
Oral microbiota: findings, classification, clinical significance, and therapeutic interventions for human systemic diseases ABSTRACT The oral microbiota is an ecological community of commensal, symbiotic, and pathogenic microorganisms that colonizes the oral cavity.
Miao Zhang +13 more
wiley +1 more source
A hidden battle in the dirt: Soil amoebae interactions with Paracoccidioides spp.
Paracoccidioides spp. are thermodimorphic fungi that cause a neglected tropical disease (paracoccidioidomycosis) that is endemic to Latin America. These fungi inhabit the soil, where they live as saprophytes with no need for a mammalian host to complete ...
Patrícia Albuquerque +17 more
doaj +1 more source
Structural diversity and biological significance of glycosphingolipids in pathogenic and opportunistic fungi [PDF]
Glycosphingolipids (GSLs) are ubiquitous membrane components and have key roles in biological systems, acting as second messengers or modulators of signal transduction by affecting several events, ranging from cell adhesion, cell growth, cell motility ...
Anita Hilda Straus +5 more
core +2 more sources
Paracoccidioides brasiliensis: phylogenetic and ecological aspects [PDF]
The knowledge on the biological aspects of Paracoccidioides brasiliensis has evolved greatly since the first description of the disease in 1908. From the pioneers, who were able to clearly demonstrate the fungal nature of the agent, to the recent genomic era, important advances have been achieved. P.
Bagagli, Eduardo +3 more
openaire +3 more sources
The Emerging Role of Microbial Extracellular Vesicles in Neuroinflammation and Neurodegeneration
ABSTRACT Neurodegenerative and neuropsychiatric disorders are increasingly viewed as systemic conditions shaped by interactions among peripheral immunity, microbiota, and the central nervous system. However, the mechanisms linking microbial activity to neuroinflammation and neurodegeneration remain poorly defined.
Julio Jesús Estrada‐Valbuena +3 more
wiley +1 more source
Ever since the uncultivated South American fungal pathogen Lacazia loboi was first described 90 years ago, its etiology and evolutionary traits have been at the center of endless controversies.
Raquel Vilela +6 more
doaj +1 more source

