Results 31 to 40 of about 6,588 (165)
Clinical features and genetic background of the sympatric species Paracoccidioides brasiliensis and Paracoccidioides americana. [PDF]
PLoS Neglected Tropical Diseases, 2019 INTRODUCTION:The agents of paracoccidioidomycosis, historically identified as Paracoccidioides brasiliensis, are in fact different phylogenetic species.
Priscila Marques de Macedo +5 more
doaj +1 more source
Infrared Spectroscopy as a Promising Tool for Diagnosing and Typing Human Pathogenic Fungi
Mycoses, Volume 69, Issue 1, January 2026.ABSTRACT Fungal infections are increasingly recognised as a global health challenge, responsible for millions of cases annually and substantial mortality, especially in immunocompromised individuals. Yet, the diagnosis of these infections remains notoriously difficult, often delayed by slow culture‐based methods or hindered by the high cost and ...
Anthony G. J. Medeiros +8 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2015 BackgroundHypoxic microenvironments are generated during fungal infection. It has been described that to survive in the human host, fungi must also tolerate and overcome in vivo microenvironmental stress conditions including low oxygen tension; however ...
Patrícia de Sousa Lima +4 more
doaj +1 more source
Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez +3 more
wiley +1 more source
Global Challenges, Volume 9, Issue 12, December 2025.This study integrates computational and experimental approaches to explore how short dipeptides modulate the activity of chorismate synthase. Unexpectedly, the GluAsp dipeptide enhanced enzyme activity by promoting a transient surface channel near the active site, possibly revealing a new structural feature relevant for microbial metabolism and ...
Lorenzo Pedroni +4 more
wiley +1 more source
Journal of Fungi, 2022 Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Brazil. The disease is caused by dimorphic fungi nested within the Paracoccidioides genus.
Alessandra G. Krakhecke-Teixeira +10 more
doaj +1 more source
Fungal DNA‐barcoding on a chip: Magnetoresistive biosensors for yeast infection diagnosis
VIEW, Volume 6, Issue 6, December 2025.The development of a fungal pathogen identification chip is herein demonstrated. Hybridization dynamics were tested against 58 species in silico and 4 species on chip. 95% accuracy, 91% sensitivity, 98% specificity and femtomolar limit of detection were achieved. Future perspectives include the integration of sample pre‐treatment modules.
Maria Zolotareva +8 more
wiley +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
Immunology, Volume 176, Issue 3, Page 277-303, November 2025.The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder +4 more
wiley +1 more source
A hidden battle in the dirt: Soil amoebae interactions with Paracoccidioides spp.
PLoS Neglected Tropical Diseases, 2019 Paracoccidioides spp. are thermodimorphic fungi that cause a neglected tropical disease (paracoccidioidomycosis) that is endemic to Latin America. These fungi inhabit the soil, where they live as saprophytes with no need for a mammalian host to complete ...
Patrícia Albuquerque +17 more
doaj +1 more source
Transcriptional and proteomic responses to carbon starvation in Paracoccidioides. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND: The genus Paracoccidioides comprises human thermal dimorphic fungi, which cause paracoccidioidomycosis (PCM), an important mycosis in Latin America. Adaptation to environmental conditions is key to fungal survival during human host infection.
Patrícia de Sousa Lima +5 more
doaj +1 more source